Photodynamic therapy for keloids and hypertrophic scars: a review

Tosa, Mamiko; Ogawa, Rei

doi:10.1177/2059513120932059

Cited by 21 publications

(23 citation statements)

References 39 publications

(61 reference statements)

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“…Consequently, existing scars can be improved by applying fixation tape or gel sheets. It has been formally shown that gel sheets can reduce local skin tension on keloids and hypertrophic scars [47–49]. Fixation tape and gel sheets can also promote scar maturation by moderately moisturizing the surface of the scar [33].…”

Section: Main Contextmentioning

confidence: 99%

“…27) Concept Compression therapy has long been used to treat hypertrophic scars that arise from burns [52, 53]. It is also widely used as a conservative treatment for keloids and hypertrophic scars in general [48, 49, 54–56]. This therapy is believed to act by placing pressure on the blood vessels in and near the scar.…”

Section: Main Contextmentioning

confidence: 99%

“…Therefore, in summer, it may be necessary to choose a compressive material that had good ventilation.Bandages and the gum of compression garments may induce itching. If itching arises, the use of these compressive materials should be stopped temporarily [49]. Goal The goal of compression therapy is to improve objective scar symptoms such as redness.Compression therapy can also be used to prevent keloids and hypertrophic scars from arising after surgery.…”

Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

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Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

et al. 2019

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There has been a long-standing need for guidelines on the diagnosis and treatment of keloids and hypertrophic scars that are based on an understanding of the pathomechanisms that underlie these skin fibrotic diseases. This is particularly true for clinicians who deal with Asian and African patients because these ethnicities are highly prone to these diseases. By contrast, Caucasians are less likely to develop keloids and hypertrophic scars, and if they do, the scars tend not to be severe. This ethnic disparity also means that countries vary in terms of their differential diagnostic algorithms. The lack of clear treatment guidelines also means that primary care physicians are currently applying a hotchpotch of treatments, with uneven outcomes. To overcome these issues, the Japan Scar Workshop (JSW) has created a tool that allows clinicians to objectively diagnose and distinguish between keloids, hypertrophic scars, and mature scars. This tool is called the JSW Scar Scale (JSS) and it involves scoring the risk factors of the individual patients and the affected areas. The tool is simple and easy to use. As a result, even physicians who are not accustomed to keloids and hypertrophic scars can easily diagnose them and judge their severity. The JSW has also established a committee that, in cooperation with outside experts in various fields, has prepared a Consensus Document on keloid and hypertrophic scar treatment guidelines. These guidelines are simple and will allow even inexperienced clinicians to choose the most appropriate treatment strategy. The Consensus Document is provided in this article. It describes (1) the diagnostic algorithm for pathological scars and how to differentiate them from clinically similar benign and malignant tumors, (2) the general treatment algorithms for keloids and hypertrophic scars at different medical facilities, (3) the rationale behind each treatment for keloids and hypertrophic scars, and (4) the body site-specific treatment protocols for these scars. We believe that this Consensus Document will be helpful for physicians from all over the world who treat keloids and hypertrophic scars.

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Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

Section: Main Contextmentioning

confidence: 99%

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Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

et al. 2019

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Efficacy of surgery combined with photodynamic therapy or triamcinolone acetonide for keloid treatment: An interim analysis of nine cases

Lin

Hao

et al. 2022

Transl Biophotonics

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Photodynamic therapy emerged in the 1900s and recently, it has been developed as a novel modality for treating tumors, precancerous lesions, hypertrophic skin diseases, vascular diseases and so on. We aimed to compare the efficacy and adverse effects of surgery combined with photodynamic therapy or triamcinolone acetonide injection for keloid treatment. This self-controlled study included nine patients with keloids. Two keloid sites were selected for each patient: one site received photodynamic therapy (PDT group) and the other site received local triamcinolone acetonide injections (TA group). All the keloids were surgically excised. The Vancouver Scar Scale and pruritus and pain scores were assessed at 3 and 6 months, respectively. At 3 and 6 months postoperatively, the pruritus and pain scores decreased significantly (P < .01) and equally in both groups (P > .05). At 6 months postoperatively, the PDT group showed the following results: complete cure, one patient; significantly effective, four patients; effective, four patients; and ineffective, no patient (efficacy, 100%). The TA group showed the following results: complete cure, one patient; significantly effective, three patients; effective, four patients; and ineffective, one patient (efficacy, 88.9%). Between-group differences were not significant (P > .05). Hyperpigmentation was observed (n = 2) in the experimental group, whereas menstrual disorders (n = 2), local capillary dilation (n = 1) and subcutaneous atrophy (n = 1) were observed in the TA group. Photodynamic therapy and local triamcinolone acetonide are equally Xie Fang, Li Cheng-xin, Qi Jing and Lin Xing-xiao have contributed equally to this work.Qi Jing and Lin Xing-xiao should be considered joint first author.

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Photodynamic Therapy for the Treatment of Scars

Shokrollahi

Hardman

2020

Laser Management of Scars

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Photodynamic therapy for keloids and hypertrophic scars: a review

Cited by 21 publications

References 39 publications

Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

Efficacy of surgery combined with photodynamic therapy or triamcinolone acetonide for keloid treatment: An interim analysis of nine cases

Photodynamic Therapy for the Treatment of Scars

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