Photodynamic inactivation of Enterococcus faecalis by conjugates of zinc(II) phthalocyanines with thymol and carvacrol loaded into lipid vesicles

Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine

“…The bioluminescence is correlated with the level of metabolism and, finally, cell viability. Microtox test can be used to determine the potential toxicity of the assessed materials and photosensitizers, which has been presented many times recently [32,41,59]. Suspensions of all obtained nanoparticles were prepared for the test: levan-coated nanoparticles (Lev-Fe 3 O 4 ), levan, and photosensitizer (Lev-ZnPc-Fe 3 O 4 ), as well as neat magnetite nanoparticles (Fe 3 O 4 ).…”

“…In the presented study, consideration is given to the synthesis of the The properties of the nanoparticles were examined in terms of magnetization and the ability to produce singlet oxygen in an aqueous medium, which are necessary for the effectiveness of PDT-hyperthermia combined therapy. Finally, the preliminary toxicity of neat levan and all prepared nanoparticles were studied both under and without light irradiation using Microtox® test, which has been so far applied for the toxicity assessment of many porphyrazine and phthalocyanine photosensitizers [4,[31][32][33][34].…”

Dual-purpose zinc and silicon complexes of 1,2,3-triazole group substituted phthalocyanine photosensitizers: synthesis and evaluation of photophysical, singlet oxygen generation, electrochemical and photovoltaic properties

“…A promising photosensitizer should have the ability to perform an efficient intersection transition so that it can transfer energy to underground-state molecular oxygen. 7,8 Phthalocyanines are the leading photosensitizers with this property. The rst step in PDT treatments is to synthesize suitable photosensitizers and to evaluate the photophysical and photochemical properties of this photosensitizers and to test its usability for the PDT.…”

Novel Water-Soluble Silicon(IV) Phthalocyanine for Photodynamic Therapy and Antimicrobial Inactivations

“…[26] This allows to image the bacterial biofilms so that to distinguish from the native fluorescence of the cell chromophores. [27] The laser scanning of the biomass (l exc = 488 nm; l em = 500-580 nm) showed the native 48-h biofilm as is shown in Figure 10A (green channel). The collected samples were evaluated at excitation laser l exc = 633 nm to obtain the fluorescence emission spectrum l em = 660-740 nm for detection of compound 3Q ( Figure 10B, red channel).…”