Photochemical syntheses of 2-heterobicyclo-(3.2.0)heptane and-(4.2.0)octane ring systems.

Rapid and Scalable Access into Strained Scaffolds through Continuous Flow Photochemistry

“…Application of identical conditions to the homologous precursor 6b worked equally well, albeit that a slightly longer residence time of 40 min was required to reach full conversion to the “straight” photocycloadduct 9 . Again, an excellent yield is obtained after chromatography (95%); however, the product appeared not fully stable.…”