Photochemical reaction detection of phylloquinone and menaquinones. A comparison with chemical post-columns reduction for fluorescence detection

Lefevere, M.F.; Frei, R.W.; Scholten, A.H.M.T.; Brinkman, U.A.Th.

doi:10.1007/bf02261609

Cited by 42 publications

(15 citation statements)

References 21 publications

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“…Electrochemical detection (108,109) offers increased sensitivity but is unstable and difficult to use in a reductive mode. The reduced form of vitamin K, the naphthohydroquinone, is fluorescent, and increased sensitivity has been achieved by postcolumn chemical reduction of the vitamin, photochemical reduction or electrochemical reduction (110,111). In all cases, the reduced (116,117) have demonstrated that the intravenous injection of a small amount of plasma obtained from a rabbit with a low level of vitamin K-dependent clotting factors into a normal rabbit will result in an increase in the activities of these factors in the recipient rabbit.…”

Section: Suttie Hepatologymentioning

confidence: 99%

Recent advances in hepatic vitamin k metabolism and function

Suttie

1987

Hepatology

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Section: Suttie Hepatologymentioning

confidence: 99%

Recent advances in hepatic vitamin k metabolism and function

Suttie

1987

Hepatology

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“…In these case, anaerobic photoreduction reactions of sensitizers such as aromatic ketones by hydrogen atom donating (HAD) compounds like aliphatic alcohols, aldehydes, saccharides, glycosides, amines and steroides are generally used [155][156][157][158][159]. Aromatic ketones including quinone [156,157] and anthraquinone derivatives [155,158,159] …”

Section: Photosensitized Fluorimetric (Psf) Methodsmentioning

confidence: 99%

“…An advantage of the photosentized fluorimetric (PSF) method is that it can be applied either to the detection of HAD compounds [155,158] or to that of quinones themselves [156,157].…”

Section: Dossiermentioning

confidence: 99%

Luminescence methods in pesticide analysis. Applications to the environment

Aaron¹,

Coly²

2000

Analusis

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DossierLuminescence spectroscopy such as the need for pretreatment procedures in the case of weakly volatile and/or thermally labile pesticides (e.g., carbamates, phenylureas and sulfonylureas). The second most utilized method is HPLC, with UV-visible absorption detectors; it remains the technique of choice for screening work.The use of luminescence techniques (especially fluorescence) for organic pesticide residue analysis has been limited by the fact that, relatively few of these compounds are strongly luminescent. However, many compounds do possess the necessary degree of aromaticity and may be converted into luminescent species using a variety of methods. Hence, two distinct cases have to be considered. (i) If the pesticide under study is luminescent, then it can be determined directly; (ii) if the pesticide is non or weakly luminescent, it can be converted into a luminescent compound using various physicochemical means, including chemical and/or photochemical reactions.Derivatization reactions constitute an important aspect of pesticide luminescence analysis since many pesticides have one or more functional groups and can be converted into more stable derivatives to successfully ensure environmental analysis. The number of papers, especially reviews [8][9][10][11][12][13] and books [14][15][16][17], in which this subject is discussed, demonstrates this increase of the derivatization use.In this review, the most important publications concerning significant advances in the luminescence methodology, instrumentation and applications to environmental analysis of pesticides will be reported. We will describe the recent available literature on direct and indirect fluorimetric methods, photochemically-induced fluorescence, photosensitized fluorescence and phosphorimetric methods used for pesticide analysis. As it will be shown, recent instrumentation, including sophisticated electronics and precise optical systems, makes luminescence a highly sensitive and selective tool for pesticide residue detection. Fluorimetric methodsAn early work on the fluorescence of pesticides has been performed in stationary solutions, (i.e., batch procedure) by

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“…5 Recently, packed columns with powdered zinc and post-column derivatization procedures in chromatography have been used. 6 Both electrochemical 7,8 and photochemical reduction 9 have been exploited for fluorimetric detection. Other methods include spectrophotometric detection, 10,11 HPLC 12 and polarographic determination of menadione in anhydrous acetonitrile with lithium perchlorate as carrier electrolyte against a calomel reference electrode.…”

mentioning

confidence: 99%

Spectrofluorimetric Determination of Vitamin K3 by a Solid-phase Zinc Reactor Immobilized in a Flow Injection Assembly

Torró¹,

Mateo²,

Calatayud³

1997

Analyst

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The spectrofluorimetric determination of vitamin K3 (menadione) using a flow injection (FI) assembly provided with a solid-phase reactor with immobilized zinc is described. The naphthohydroquinone was produced by means of two coupled steps in the FI system: hydrolysis of the sodium sulfite derivative of the menadione in a basic medium and reduction of the generated menadione in the zinc reactor in an acidic medium. The fluorescent product was monitored spectrofluorimetrically (lambda ex 325 nm; lambda em 425 nm). The calibration graph was linear over the range 0.1-18 micrograms ml-1 with a reproducibility of 1.6%; the limit of detection was 0.005 microgram ml-1 and the sample throughput was 70 h-1. The influence of foreign compounds was studied and the procedure was applied to the determination of vitamin K3 in three different pharmaceutical formulations.

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Photochemical reaction detection of phylloquinone and menaquinones. A comparison with chemical post-columns reduction for fluorescence detection

Cited by 42 publications

References 21 publications

Recent advances in hepatic vitamin k metabolism and function

Recent advances in hepatic vitamin k metabolism and function

Luminescence methods in pesticide analysis. Applications to the environment

Spectrofluorimetric Determination of Vitamin K3 by a Solid-phase Zinc Reactor Immobilized in a Flow Injection Assembly

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