Photocatalytic treatment of metoprolol and propranolol

Photocatalytic degradation of metoprolol tartrate in suspensions of two TiO2-based photocatalysts with different surface area. Identification of intermediates and proposal of degradation pathways

“…Intermediate 2 was also identified by Yang et al and Romero et al [19,20]. The attack of • OH on the C atom next to the ether oxygen and the oxidation of the hydroxyl group would yield the ketotautomer 3, which forms two peaks at retention times 2.09 and 3.60 min (Fig.…”

“…Yang et al investigated the degradation of selected β-blockers (atenolol, metoprolol and propranolol) in aqueous suspensions of TiO 2 Degussa P25 and proposed a preliminary mechanism of degradation of these compounds [19]. Romero et al have also investigated and compared the degradation intermediates of metoprolol and propranolol by AOPs [20].…”

“…The attack of the • OH on the C atoms of the aromatic ring of compound 3 yielded the hydroxy (4) and dihydroxy (5) proposed a different structure that involved the opening of the aromatic ring [20]. could take place, thus one might expect to find two chromatographic 13 peaks as in the case of 7.…”

Photocatalysis of β-blockers – An overview

“…Natural radical scavengers present in the river water reduce the HO Å concentration and thereby decreasing the photocatalytic efficiency. Romero et al (2011) investigated the degradation of metoprolol and propranolol by photocatalysis. Photocatalytic experiments were carried out with 0.4 g/L of TiO 2 as catalyst, 50 mg/L of both drugs and xenon lamp as irradiation source.…”

Hybrid nanoadsorbents for the magnetically assisted removal of metoprolol from water

“…Several processes have been proposed for the elimination and degradation of MTP from water, including advanced oxidation processes [7,8], photocatalytic treatment [9]- [11] and adsorption [12]- [14]. Compared to other methods, adsorption is an attractive process in view of its simplicity of implementation and low cost.…”