Photocatalytic decarboxylative alkylations of C(sp3)-H and C(sp2)-H bonds enabled by ammonium iodide in amide solvent

Metal-free C–Se cross-coupling enabled by photoinduced inter-molecular charge transfer

“…Moreover, the addition of 10 mol% of TBAI as an additive is beneficial for the transformation (entry 8). [30][31] w/o blue LED 0 a Reaction conditions: 1a (0.20 mmol), 2a (0.40 mmol), DBU (2 equiv.) in DMF (1 mL) was irradiated under 440 nm blue LED at rt.…”

Electrochemically-mediated C–H functionalization of allenes and 1,3-dicarbonyl compounds to construct tetrasubstituted furans

“…6,7 These valuable tetrasubstituted furan derivatives can be synthesized by two methods: one is the functionalization of existing furan rings, 8,9 and the other is the cyclization of acyclic substrates to construct furan rings. [10][11][12][13][14] Although the functionalization of furans seems to be an attractive approach, significant challenges remain in terms of reaction scope and chemoselectivity. The classical synthesis methods for tetrasubstituted furans include Paal-Knorr cyclocondensation (from 1,4-dicarbonyl compounds) 15,16 and Feist-Bénary cyclocondensation (from α-haloketones and β-dicarbonyl compounds).…”

Visible Light-Induced Sulphide Anion-Catalysed Decarboxylative Alkylations in Batch and Continuous Flow

“…(2-isocyanophenyl)(methyl)sulphane [30] (33), ethene-1,1-diyldibenzene [31] (34) and arylglycine derivatives and peptides [32] (35 -37). It was found that all of these compounds could undergo photoinduced decarboxylation to yield alkylation products in moderate to good yields.…”