Photocatalytic Carbon Dots‐Triggered Pyroptosis for Whole Cancer Cell Vaccines
Quansheng Cheng,
Tesen Zhang,
Qingcheng Wang
et al.
Abstract:Manufacturing whole cancer cell vaccines (WCCV) with both biosafety and efficacy is crucial for tumor immunotherapy. Pyroptotic cancer cells, due to their highly immunogenic properties, present a promising avenue for the development of WCCV. However, the successful development of WCCV based on pyroptotic cancer cells is yet to be accomplished. Here, a facile strategy that utilized photocatalytic carbon dots (CDs) to induce pyroptosis of cancer cells for fabricating WCCV is reported. Photocatalytic CDs are capa… Show more
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