Photobiomodulation in diabetic wound healing: A review of red and near‐infrared wavelength applications

Oyebode, Olajumoke A.; Houreld, Nicolette Nadene; Abrahamse, Heidi

doi:10.1002/cbf.3629

Cited by 32 publications

(17 citation statements)

References 135 publications

(126 reference statements)

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“…NIR irradiation has been widely used in medical use, especially for assisting wound healing ( 70 ). It is well known that the NIR light source can be absorbed into the mitochondria and promote mitochondrial respiration and adenosine triphosphate production ( 71 ).…”

Section: Resultsmentioning

confidence: 99%

Combinatorial wound healing therapy using adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation

et al. 2022

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Wound healing is the dynamic tissue regeneration process replacing devitalized and missing tissue layers. With the development of photomedicine techniques in wound healing, safe and noninvasive photobiomodulation therapy is receiving attention. Effective wound management in photobiomodulation is challenged, however, by limited control of the geometrical mismatches on the injured skin surface. Here, adhesive hyaluronic acid–based gelatin nanofibrous membranes integrated with multiple light-emitting diode (LED) arrays are developed as a skin-attachable patch. The nanofibrous wound dressing is expected to mimic the three-dimensional structure of the extracellular matrix, and its adhesiveness allows tight coupling between the wound sites and the flexible LED patch. Experimental results demonstrate that our medical device accelerates the initial wound healing process by the synergetic effects of the wound dressing and LED irradiation. Our proposed technology promises progress for wound healing management and other biomedical applications.

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Section: Resultsmentioning

confidence: 99%

Combinatorial wound healing therapy using adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation

et al. 2022

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“…One of the well-known effects of PBM is an overall inhibition of inflammation, as evidenced in various inflammatory conditions, such as diabetic wounds [ 94 ], retinal diseases [ 95 ], asthma [ 96 ], and the aging brain [ 72 ]. PBM exerts its anti-inflammatory effect by reducing many cytokines and inflammatory mediators in different inflammatory conditions such as carrageenan-induced paw edema, blepharitis, and osteoarthritis [ 10 , 97 , 98 ].…”

Section: Pbm Overviewmentioning

confidence: 99%

Therapeutic Potential of Photobiomodulation for Chronic Kidney Disease

Bean

Liebert

Bicknell

et al. 2022

IJMS

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Chronic kidney disease (CKD) is a growing global public health problem. The implementation of evidence-based clinical practices only defers the development of kidney failure. Death, transplantation, or dialysis are the consequences of kidney failure, resulting in a significant burden on the health system. Hence, innovative therapeutic strategies are urgently needed due to the limitations of current interventions. Photobiomodulation (PBM), a form of non-thermal light therapy, effectively mitigates mitochondrial dysfunction, reactive oxidative stress, inflammation, and gut microbiota dysbiosis, all of which are inherent in CKD. Preliminary studies suggest the benefits of PBM in multiple diseases, including CKD. Hence, this review will provide a concise summary of the underlying action mechanisms of PBM and its potential therapeutic effects on CKD. Based on the findings, PBM may represent a novel, non-invasive and non-pharmacological therapy for CKD, although more studies are necessary before PBM can be widely recommended.

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“…The challenge of antimicrobial resistance in treating these infections increases the complications and burden of these wounds [14,15]. Repetitive trauma, which is common in diabetic foot ulcers, can also delay or even stop the wound healing process [16]. Closed wounds include contusions (caused by a blunt force trauma that damages tissue under the skin), haematomas (accumulation of blood under skin due to a damaged blood vessel) and crush injuries (occurs when great external force is applied on the skin over a long period of time) [17].…”

Section: Classification Of Woundsmentioning

confidence: 99%

Wound Healing Activities and Potential of Selected African Medicinal Plants and Their Synthesized Biogenic Nanoparticles

Tyavambiza

Dube

Goboza

et al. 2021

Plants

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In Africa, medicinal plants have been traditionally used as a source of medicine for centuries. To date, African medicinal plants continue to play a significant role in the treatment of wounds. Chronic wounds are associated with severe healthcare and socio-economic burdens despite the use of conventional therapies. Emergence of novel wound healing strategies using medicinal plants in conjunction with nanotechnology has the potential to develop efficacious wound healing therapeutics with enhanced wound repair mechanisms. This review identified African medicinal plants and biogenic nanoparticles used to promote wound healing through various mechanisms including improved wound contraction and epithelialization as well as antibacterial, antioxidant and anti-inflammatory activities. To achieve this, electronic databases such as PubMed, Scifinder® and Google Scholar were used to search for medicinal plants used by the African populace that were scientifically evaluated for their wound healing activities in both in vitro and in vivo models from 2004 to 2021. Additionally, data on the wound healing mechanisms of biogenic nanoparticles synthesized using African medicinal plants is included herein. The continued scientific evaluation of wound healing African medicinal plants and the development of novel nanomaterials using these plants is imperative in a bid to alleviate the detrimental effects of chronic wounds.

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Photobiomodulation in diabetic wound healing: A review of red and near‐infrared wavelength applications

Cited by 32 publications

References 135 publications

Combinatorial wound healing therapy using adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation

Combinatorial wound healing therapy using adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation

Therapeutic Potential of Photobiomodulation for Chronic Kidney Disease

Wound Healing Activities and Potential of Selected African Medicinal Plants and Their Synthesized Biogenic Nanoparticles

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