Photobiomodulation for multiple sclerosis in animal models

Tolentino, Miguel; Lyons, Joseph

doi:10.1016/b978-0-12-815305-5.00019-1

Cited by 2 publications

(2 citation statements)

References 62 publications

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“…In vitro studies are poorly informative. Although illumination (λ = 830 nm, PD 10 mW/cm 2 , exposure 5min) decreases nitrite production and modulates the release of IL-10 and γ-interferon by peripheral blood mononuclear cells isolated from disseminated sclerosis patients [ 44 , 45 ], identical patterns in the clinic should not be expected for many reasons, especially if illuminated by multicolored bulbs and “doses” [ 46 ].…”

Section: Literature Reviewmentioning

confidence: 99%

A Brief Literature Review of Low-Level Laser Therapy for Treating Amyotrophic Lateral Sclerosis and Confirmation of its Effectiveness

Moskvin

2024

BioMedicine

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Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a steadily progressive course due to the death of central and peripheral motor neurons responsible for voluntary movements. Low-level laser therapy (LLLT) is a treatment method unique in its universality and efficacy, particularly for neurodegenerative diseases. Methods In this review, we discuss the effect and application of LLLT in the treatment of ALS. A literature search for English and Russian publications for the keywords “Amyotrophic Lateral Sclerosis”, “Low-Level Laser Therapy” was performed using PubMed, Scopus, Google Scholar, Web of Science and Russian Science Citation Index (RSCI) databases. Results The article provided a brief literature review, substantiated the potential use of low-level laser therapy for ALS. The particular techniques of LLLT were developed. Conclusion Based on the results of several studies and many years of successful experience with low-level laser therapy in Russia we conclude that a LLLT technique, including intravenous laser blood illumination (ILBI), noninvasive laser blood illumination (NLBI), and local exposure, is a promising treatment method for ALS.

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Section: Literature Reviewmentioning

confidence: 99%

A Brief Literature Review of Low-Level Laser Therapy for Treating Amyotrophic Lateral Sclerosis and Confirmation of its Effectiveness

Moskvin

2024

BioMedicine

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“…Today, the use of PBM to treat many diseases such as osteoporosis, wound healing, muscle problems, inflammatory pain, periodontal diseases, lung inflammation, nervous system injuries and autoimmune diseases is in the spotlight as a non-invasive treatment. 23,27,[40][41][42][43][44] PBM have been well documented in previous studies to have beneficial therapeutic effects on neurodegenerative diseases such as SCI, stroke, and traumatic brain injury. 8,21,31 The researchers of these studies have mentioned that PBM is a promising and novel treatment that can reduce neurological complications.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Effects of Photobiomodulation Therapy on Multiple Sclerosis by Regulating the Inflammatory Process and Controlling Immune Cell Activity: A Novel Promising Treatment Target

et al. 2022

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Introduction: Multiple sclerosis (MS) is one of the autoimmune and chronic diseases of the central nervous system; this disease occurs more frequently in young people and women and leads to neurological symptoms. Oxidative stress, inflammatory processes, and oligodendrocyte dysfunction have a pivotal role in the pathophysiology of this disease. Nowadays it is reported that photobiomodulation (PBM) as a non-invasive treatment has neuroprotective potential, but the exact mechanisms are not understood. Methods: In this study, we reviewed the effects of PBM on MS. In this regard, we used the keywords "Photobiomodulation", "Laser therapy", and "Low-level laser therapy" on MS to find related studies on this subject in PubMed, Google scholar, Elsevier, Medline, and Scopus databases. Results: PBM has positive effects on MS by regulating the inflammatory process, controlling immune cell activity and mitochondrial functions, as well as inhibiting free radicals production which finally leads to a reduction in neurological defects and an improvement in the functional status of patients. Conclusion: Overall, researchers have suggested the use of laser therapy in neurodegenerative diseases due to its numerous therapeutic effects.

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Photobiomodulation for multiple sclerosis in animal models

Cited by 2 publications

References 62 publications

A Brief Literature Review of Low-Level Laser Therapy for Treating Amyotrophic Lateral Sclerosis and Confirmation of its Effectiveness

A Brief Literature Review of Low-Level Laser Therapy for Treating Amyotrophic Lateral Sclerosis and Confirmation of its Effectiveness

Therapeutic Effects of Photobiomodulation Therapy on Multiple Sclerosis by Regulating the Inflammatory Process and Controlling Immune Cell Activity: A Novel Promising Treatment Target

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