1972
DOI: 10.1001/archderm.106.5.741
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Photoallergy. A review

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Cited by 35 publications
(11 citation statements)
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“…In UVA irradiated rats, covalent binding to epidermal lipids and proteins was found, but not to DNA/RNA. It is widely accepted that the photochemical binding of photoallergens, such as CPZ, to proteins is involved in the induction of photoallergic responses (Epstein, 1972;Kochevar, 197')). Photobinding of CPZ(-metabolites) to lipids could play a role in CPZ-induced phototoxicity (Schoonderwoerd and Beijersbergen van Henegouwen, 1987).…”
Section: Introductionmentioning
confidence: 99%
“…In UVA irradiated rats, covalent binding to epidermal lipids and proteins was found, but not to DNA/RNA. It is widely accepted that the photochemical binding of photoallergens, such as CPZ, to proteins is involved in the induction of photoallergic responses (Epstein, 1972;Kochevar, 197')). Photobinding of CPZ(-metabolites) to lipids could play a role in CPZ-induced phototoxicity (Schoonderwoerd and Beijersbergen van Henegouwen, 1987).…”
Section: Introductionmentioning
confidence: 99%
“…This may trigger off a cell-mediated response similar to that seen in allergic contact dermatitis with or without the necessity for further involvement of light (Willis & Khgman, 1968). The term photoallergy tends to be used in this instance (Epstein, 1972), the appearance of reaction being that of eczema (dermatitis) with or without some urticarial or erythematous elements. Some photoactive substances are able to produce both a phototoxic and a photoallergic response.…”
Section: Idiopathic Photodermatosesmentioning
confidence: 99%
“…Induction of photoallergy is widely accepted as occurring along the following lines [ 1,2]. After the initial absorption of photoallergen by the skin, excitation by light of the appropriate wavelength gives rise to a reactive species which then binds chemically to proteins in the skin.…”
Section: Introductionmentioning
confidence: 99%