Photoacoustic spectroscopy evaluation of the impact of smoking on the composition of exhaled air in patients with bronchopulmonary diseases

Bukreeva, Ekaterina; Bulanova, Anna A.; Kistenev, Yury V.; Nikiforova, O. Yu.

doi:10.17116/terarkh201789334-37

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…[31,145] The effect of non-smoking and smoking COPD and asthma patients exhaled breath was investigated by using PAS. [146] TDLAS-based NO detection system with QCL as a laser source has been demonstrated with the detection limit of 0.5 ppb and response time of ≈ 1 s for COPD and asthma detection application. [147,148]…”

Section: Asthmamentioning

confidence: 99%

Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Ranu,

Rahman

et al. 2023

Advanced Sensor Research

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Exhaled breath analysis is considered an effective tool for diagnosing the patient's metabolic status because of its non‐invasive nature. Gas chromatography‐mass spectrometry (GC‐MS) and other mass spectrometry techniques are widely used for exhaled breath analysis. Nevertheless, the requirement of a handheld device for real‐time analysis and rapid processing time of multiple samples leads to advancing infrared (IR) based breath gas sensing techniques. Herein, the IR gas sensing technologies are discussed with a focus on non‐dispersive infrared (NDIR), photoacoustic (PAS), and tunable diode laser absorption spectroscopy (TDLAS) gas sensing technologies because of their highly selective gas detection among compound gases (mixture of VOCs), as well as their corresponding sensing mechanisms and characteristics, for real‐time monitoring of exhaled biomarkers. Carbon dioxide, acetone, ammonia, nitric oxide, methane, and ethylene are the significant biomarkers elaborated in this work with their respective clinical applications and the significance of non‐invasive real‐time monitoring using IR detectors. Challenges in selectivity and clinical trials leads to focus on this review. Current market analysis, present status of different techniques to detect specific biomarkers and other challenges with their possible solutions discussed in this review aid in developing highly selective IR‐based handheld breath VOC analyzers for early diagnosis and screening.

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Section: Asthmamentioning

confidence: 99%

Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Ranu,

Rahman

et al. 2023

Advanced Sensor Research

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“…Cigarette smoking represents the major risk factor in the development of lung cancer, which is the main cause of cancer deaths in men and women in the world [141]. Bukreeva et al investigated the impact of smoking on the air exhaled by patients with chronic obstructive pulmonary disease (COPD) and asthma, by using PAS [142]. The exhaled breath absorption spectra from the subjects with COPD and asthma were compared with those from non-smoking healthy individuals.…”

Section: Lpas In Smokersmentioning

confidence: 99%

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

et al. 2020

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In this review, applications of near-infrared photoacoustic spectroscopy are presented as an opportunity to evaluate human respiration because the measurement of breath is fast, intact and simple to implement. Recently, analytical methods for measuring biomarkers in exhaled air have been extensively developed. With laser-based photoacoustic spectroscopy, volatile organic compounds can be identified with high sensitivity, at a high rate, and with very good selectivity. The literature review has shown the applicability of near-infrared photoacoustic spectroscopy to one of the problems of the real world, i.e., human health. In addition, the review will consider and explore different breath sampling methods for human respiration analysis.

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Photoacoustic spectroscopy evaluation of the impact of smoking on the composition of exhaled air in patients with bronchopulmonary diseases

Cited by 2 publications

References 8 publications

Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

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