Photoacoustic identification of blood vessel deformation under pressure

Abstract

In this work we demonstrate a photoacoustic system which can identify the deformation of blood vessels under external pressure. Using photoacoustic imaging method, the vessel internal diameter can be derived from the peak-to-peak time interval of the laser (532nm) induced the photoacoustic signals. Comparisons with the actual vessel inter diameter show that the relative deviation is less than 4%, which proves the validity of this method. Interestingly, we find that the axial diameter of the blood vessel and the blood volume increase monotonously with increasing transient pressure, and the laser-induced photoacoustic signal is mainly contributed by the blood inside the vessel. Our results suggest a new way for continuous monitoring of the deformation of blood vessels under pressure.

Photoacoustic method for measuring the elasticity of polydimethylsiloxane at various mixing ratios

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Deformation measurement of liquid-filled elastic tube embedded in soft material using optimal pulse width method under photoacoustic excitation

“…Photoacoustic imaging method, taking the advantage of the combination of high resolution of light and moderate penetration of ultrasound, has been intensively developed in the past few years, thanks to the fast development of the electronic circuit and transducer design [25,26]. The function of photoacoustic detection has also been expanded to the blood vessels diameter measurement recently [27,28,29,30]. It has been demonstrated that the photoacoustic measurement can reach the diameters down to 0.1 mm order by employing high power pulsed laser source and 10 MHzorder ultrasound transducer array.…”

Photoacoustic waves of a fluidic elliptic cylinder: Analytic solution and finite element method study

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