Photo-crosslinked polyaspartamide hybrid gel containing thermo-responsive Pluronic triblock copolymer

Park, Jong Hyun; Moon, Jong Rok; Hong, Kwang Hyun; Kim, Ji‐Heung

doi:10.1007/s10965-010-9415-3

Cited by 8 publications

(3 citation statements)

References 18 publications

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“…DMPA is an acetophenone derivative that is well-known to undergo α-cleavage (Norrish I) between the carbonyl carbon and the carbon bearing the methoxy groups leading to the formation of two very reactive radicals under UV-irradiation at λ = 365 nm . It is poorly soluble in water and exhibits a significant toxicity when used at relatively high concentration. , Despite these two drawbacks and because of its very high reactivity toward (meth)acrylate groups, it has been very often used for creating hydrogels of various porosities using various techniques. − …”

Section: Methodsmentioning

confidence: 99%

“…Generally, the grafting of polymerizable groups is made by reaction of hydroxyl or amine functions borne by the polymeric precursor with (meth)acryloyl chloride, (meth)acrylic anhydride, (meth)acrylic acid (in the presence of EDC and NHS), or glycidyl methacrylate. Many researchers have also associated two or more polymers to form a conetwork or interpenetrated polymer networks (IPNs). ,,,,,,,,,,,− …”

Section: Methodsmentioning

confidence: 99%

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Photopolymerized Porous Hydrogels

Nicol

2021

Biomacromolecules

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Hydrogels are polymeric networks highly swollen with water. Because of their versatility and properties mimicking biological tissues, they are very interesting for biomedical applications. In this aim, the control of porosity is of crucial importance since it governs the transport properties and influences the fate of cells cultured onto or into the hydrogels. Among the techniques allowing for the elaboration of hydrogels, photopolymerization or photo-cross-linking are probably the most powerful and versatile synthetic routes. This Review aims at giving an overview of the literature dealing with photopolymerized hydrogels for which the generation or characterization of porosity is studied. First, the materials (polymers and photoinitiating systems) used for synthesizing hydrogels are presented. The different ways for generating porosity in the photopolymerized hydrogels are explained, and the characterization techniques allowing adequate study of the porosity are presented. Finally, some applications in the field of controlled release and tissue engineering are reviewed.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Photopolymerized Porous Hydrogels

Nicol

2021

Biomacromolecules

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“…For instance, light responsive coumarin moieties were introduced to the side chains of PASPAm derivative, and the formed micelles can be conveniently cross-linked and stabilized by exposing it to the light of 365 nm for 30 min [93]. Photo-crosslinking can also be achieved by introducing methacryloyl [9,94] or acryloyl [95] moieties to the ethanolamide or hydrazide pendants of PASPAm.…”

Section: Other Stimuli-responsive Poly(aspartamide) Derivativesmentioning

confidence: 99%

Stimuli-Responsive Poly(aspartamide) Derivatives and Their Applications as Drug Carriers

Zhang

Bao

2021

IJMS

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Poly(aspartamide) derivatives, one kind of amino acid-based polymers with excellent biocompatibility and biodegradability, meet the key requirements for application in various areas of biomedicine. Poly(aspartamide) derivatives with stimuli-responsiveness can usually respond to external stimuli to change their chemical or physical properties. Using external stimuli such as temperature and pH as switches, these smart poly(aspartamide) derivatives can be used for convenient drug loading and controlled release. Here, we review the synthesis strategies for preparing these stimuli-responsive poly(aspartamide) derivatives and the latest developments in their applications as drug carriers.

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Surface modification using bio‐inspired adhesive polymers based on polyaspartamide derivatives

An¹,

Huynh²,

Jeon³

et al. 2011

Polymer International

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The catechol functional group of dopamine (3,4‐dihydroxyphenethylamine) has the ability to form strong adhesive bonds to inorganic and organic surfaces in aqueous environments. In this study, novel adhesive polyaspartamides containing catechol pendant groups were synthesized from polysuccinimide through successive aminolysis reactions with quantitative dopamine and ethylenediamine. The adhesion and crosslinking of dopamine‐modified polyaspartamide in aqueous alkaline media was used successfully to modify the surface of various materials (including synthetic polymers, metals, metal oxides, ceramics) using a simple immersion method. Contact angle measurements, SEM and X‐ray photoelectron spectroscopy of the modified surfaces were used to verify the surface coating on a variety of materials with very different inherent wetting properties. These novel biocompatible polymers have potential industrial and biomedical applications as adhesives or coating materials for functional surface modification. Copyright © 2011 Society of Chemical Industry

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Photo-crosslinked polyaspartamide hybrid gel containing thermo-responsive Pluronic triblock copolymer

Cited by 8 publications

References 18 publications

Photopolymerized Porous Hydrogels

Photopolymerized Porous Hydrogels

Stimuli-Responsive Poly(aspartamide) Derivatives and Their Applications as Drug Carriers

Surface modification using bio‐inspired adhesive polymers based on polyaspartamide derivatives

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