Photo-crosslinkable polyester microneedles as sustained drug release systems toward hypertrophic scar treatment
Anna Szabó,
Ignace De Decker,
Sam Semey
et al.
Abstract:Burn injuries can result in a significant inflammatory response, often leading to hypertrophic scarring (HTS). Local drug therapies e.g. corticoid injections are advised to treat HTS, although they are invasive, operator-dependent, extremely painful and do not permit extended drug release. Polymer-based microneedle (MN) arrays can offer a viable alternative to standard care, while allowing for direct, painless dermal drug delivery with tailorable drug release profile. In the current study, we synthesized photo… Show more
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