Phosphorylated bush sophora root polysaccharides protect the liver in duck viral hepatitis by preserving mitochondrial function

Qiu, Tianxin; Shi, Yu; He, Miao; Wang, Wenjia; Meng, Jinwu; Ding, Jinxue; Wang, Weiran; Li, Siya; Li, Kun; Liu, Jiaguo

doi:10.1016/j.ijbiomac.2023.125419

International Journal of Biological Macromolecules

2023

DOI: 10.1016/j.ijbiomac.2023.125419

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Phosphorylated bush sophora root polysaccharides protect the liver in duck viral hepatitis by preserving mitochondrial function

Tianxin Qiu,

Yu Shi,

Miao He

et al.

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2024

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Cited by 3 publications

References 33 publications

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Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

Gao,

Liu,

Dai

et al. 2024

Starch Stärke

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Polysaccharides are a kind of biological macromolecule, which widely exists in plants, fungi, animals, microorganisms, and other organisms. Polysaccharides exhibit various biological activities such as immunological regulation, antioxidation, antitumor, antiinflammatory, regulating intestinal flora, and protecting liver. These biological activities depend on their structure and physicochemical properties including monosaccharide composition, molecular weight (Mw), spatial configuration, etc. However, biological activities of polysaccharides are hardly comparable to synthetic drugs due to their inherent physicochemical properties. Therefore, structural modification of polysaccharides is an effective way to enhance their biological activities and promote the presentation of bioactivity. At present, phosphorylation modification is a common chemical modification method, which can effectively improve the biological activities of polysaccharides. However, there are limited reports on the synthesis, structure identification, and biological activities of phosphorylated polysaccharides. In view of this, the synthesis methods, structure identification methods, and biological activities of phosphorylated polysaccharides are reviewed in this paper. The findings can provide useful guidance for the research, production, and application of phosphorylated polysaccharides in functional foods and therapeutic agents.

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Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

Gao,

Liu,

Dai

et al. 2024

Starch Stärke

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Anti-virus activity and mechanisms of natural polysaccharides from medicinal herbs

Huang,

Chen,

Xian

et al. 2024

Carbohydrate Research

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Advances in the Duck Hepatitis A virus and lessons learned from those in recent years

Zhao,

Wu,

Wang

et al. 2024

Microbial Pathogenesis

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Phosphorylated bush sophora root polysaccharides protect the liver in duck viral hepatitis by preserving mitochondrial function

Cited by 3 publications

References 33 publications

Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

Anti-virus activity and mechanisms of natural polysaccharides from medicinal herbs

Advances in the Duck Hepatitis A virus and lessons learned from those in recent years

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