Phosphorus Oxychloride in Organic Synthesis. Part 3: Synthesis of α-Benzoylaminocinnamic Acids

Pd@l-asparagine–EDTA–chitosan: a highly effective and reusable bio-based and biodegradable catalyst for the Heck cross-coupling reaction under mild conditions

“…100,101 Both acid and ester forms (methyl, ethyl, and benzyl) exist in different essential oils, resins, and balsams. Although there are natural sources for CADs, various chemical and biochemical approaches have been invented for their synthesis including the Perkin reaction, 102 enzymatic method, 103 Knoevenagel condensation accelerated by MW irradiation 104 or promoted by tetraalkylammonium halides, 105 the use of phosphorous oxychloride, 106 or DDQ under ultrasonic conditions, 107 Claisen–Schmidt condensation, and HCR. 108 Among these procedures, green HCR catalyzed by biopolymeric-based catalysts has been performed recently.…”

Supramolecular Pd@methioine-EDTA-chitosan nanocomposite: an effective and recyclable bio-based and eco-friendly catalyst for the green Heck cross-coupling reaction under mild conditions

“…16 Scientic research has demonstrated that CA exhibits biological and chemical properties, including antioxidant, antimicrobial, anti-inammatory, 17,18 anticancer, 19,20 neuroprotective, 21 and antidiabetic, 22,23 as well as acting as a UV protector in cosmetics, 24 precursor of shikimic acid, an important intermediate in the pharmaceutical industry 25 and precursor of fragrance materials. 26 Although there are natural sources of CADs, several chemical and biochemical methodologies have been reported for their synthesis, including the Claisen-Schmidt condensation, 27 Perkin reaction, 28 Knoevenagel condensation promoted by tetraalkylammonium halides 29 or accelerated by MW irradiation, 30 the application of phosphorous oxychloride, 31 or DDQ under ultrasonic conditions, 32 biocatalytic synthesis, 33,34 and HCR. 1,27,35,36 Among these procedures, green HCR catalyzed by biopolymeric-based catalytic systems has been recieved graet attention recently.…”