Phosphorus Nutrition and Health: Utilization of Phytaseproducing Bifidobacteria in Food Industry

Abstract

Phosphorus plays vital roles in human health and nutrition. In nature, phosphorus exists as phosphate, either inorganic or organic. The major form of phosphate in plantderived diets is phytate that cannot be degraded by monogastric animal, as well as humans. Initially, this chapter reviews current research of phosphorus in human nutrition and health. Subsequently, problems of phytate degradation and phosphorus utilization in plant-derived diet are outlined. Next, as the main part, the enzymes of phytase, which catalyze the release of inorganic phosphorus from phytate, are compared, especially those produced by gut microbiota. Meanwhile, how probiotic bifidobacteria can be used for producing phytase and therefore enhance their beneficial effects are discussed. Phytase-producing bifidobacteria can be either isolated rarely in nature or constructed by genetic cloning of phytase genes from other well-characterized enzymes. The combination of bifidobacteria and highly active phytase may improve human health and nutrition especially as supplementary probiotic foods. Therefore, potential application is prospected. Finally, other considerations related to industrial production and usage of phosphorus-enriched additives are remarked. In conclusion, improving and maintaining the phosphorus balance in food by bifidobacteria may be promising for a healthier life.

Studying of Metal Elements in Cerebrospinal Fluid for Children With Acute Lymphoblastic Leukemia Patients

“…The result in tables (3) and (4) showed that there was a significant increase (p≤ 0.05) for phosphorus levels in CSF of patients with acute lymphoblastic leukemia for both sex and in all age group our result was in agreement with previous reports which showed the toxic effect for high level of phosphorus and its role in cancer and neurodisorders [16] the high level of Phosphorus maybe due to renal function defect for leukemia patients [46] and because of dysfunction of blood brain barrier BBB. [47] The level of phosphorus will increase in CSF, the results also showed that the levels of phosphorus increased with age and it is in male higher than female and this was in agreement with [48] and this may be due to the estrogen effect which decreases the expression of kidney sodium-phosphate co transporters.…”

“…[15] Inorganic phosphate plays significant roles in many biological processes such as cell signalling, synthesis of nucleic acid, energy metabolism, membrane functions, bone mineralisation and carbohydrate metabolism. [16] In addition, it is essential for the normal generation of red blood cells, white blood cells and platelet function. [17,18] Excessive retention of phosphate in the body is toxic to humans and can cause a wide range of cellular and tissue injuries such as:…”

Characterization of horse gram mutants for yield, nutrient, and anti-nutrient factors

“…content of 319 mg 100g . The importance of micronutrients viz., boron (Nielsen and Eckhert, 2020), magnesium (Rosanoff, 2021), phosphorus (Chen et al, 2016), potassium (Filippini et al, 2020), calcium (Pravina, 2013), manganese (Santamaria, 2008), iron (Briguglio, 2020), copper (Taylor, 2020), zinc (Santos, 2020), and molybdenum (Bell, 2021) in human health is well documented which necessitated the micronutrient profiling of mutants in the current investigation.…”

Assessment of the Nutritional Value of Selected Wild Leafy Vegetables Growing in the Roma Valley, Lesotho

“…It acts as a buffer, neutralizing acids to maintain normal pH in the blood, it is a part of DNA and RNA molecules; the genetic code of every cell, which makes it essential for cellular growth and development. These vegetables may not be a good source of P because of the low content of this mineral, coupled with the fact that the bioavailability of organic P is low as it is usually in the form of phytates, which humans are unable to digest [52].…”