PHOSPHORUS-FLUORINE CHEMISTRY PART XLII¹. PYRROLE-SUBSTITUTED FLUOROPHOSPHORANES

Phosphorylation of N‐Silylpyrroles with Phosphorus Tribromide

“…At the same time, the literature evidence refers only to phosphorylation of N-trimethylsilylpyrrole with fluorophosphoranes [3] or dimethylamidodichlorophosphite [4] that involves the pyrrole nitrogen atom and is accompanied by the trimethylsilyl halide elimination.…”

Synthesis and NMR Investigation of Phosphineiminophosphonium Organofluorophosphate Salts

“…4 Hz. Surprisingly, replacement of a methyl group at the central phosphorus in I by fluorine (II) only changes 'JPp slightly (if the sign of 2Jpp is positive throughout the series), but 2JpaH is increased by 3.6 Hz.…”

N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole

“…In continuation, the electronics of isoindoles were altered by fluorine substituents on the aromatic ring and positioning of the guanidine functionality. Tetrafluoro isoindole precursor 37 was prepared in 35% yield by mechanochemical guanylation [29] of the known 7-azabenzonorbornadiene 36 [30,31] (Scheme 5). It was found that fluorine substitution did not have noticeable effects on the cycloaddition reactivity of isoindole.…”