Phosphine‐Free NNN‐Manganese(II) Catalyzed C‐alkylation of Methyl N‐Heteroarenes via Borrowing Hydrogen

Abstract

Mn(II)‐catalyzed alkylations of methyl N‐heteroarenes was firstly reported via borrowing hydrogen strategy with alcohols as the alkylating reagent. The newly developed geometry‐constrained benzimidazole‐iminopyridyl ligand played a key role in promoting the transformation and stablizing the metal center. A wide range of alcohols (aromatic, heteroaromatic and aliphatic) and methyl N‐Heteroarenes could be able to apply in the current catalytic system, with TON up to 7400.