23 patients with Starr-Edwards aortic valve prostheses (models 1000,1200,1260,2320) were studied repeatedly at various intervals after valve replacement (2 weeks to 90 months). The aortic opening to closing (AO/AC) ratio on phonocardiograms and on sound spectrograms showed a wide range of values. A reduction in left ventricular function as indicated by altered systolic time intervals was associated with a very low phonocardiographic AO/AC ratio and/or decreased peak frequency on sound spectrograms in some patients, but there was no correlation between the AO/AC ratios and the systolic time intervals, the ejection fraction and an index of myocardial contractility (diastolic blood pressure/external isovolumic concentration time) in the group as a whole. Mild aortic paravalvular regurgitation influenced neither the AO/AC ratios nor the peak frequency of the aortic opening sound.