Phonocardiographic changes in mitral stenosis before and after valvulotomy: A correlation with mitral valve size

The Apex Cardiogram in the Study of the 2 Os Interval

“…The 2-OS interval representing the period of isometric relaxation has been studied by various authors in patients with mitral valvular disease and its usefulness has been repeatedly emphasized (Margolies and Wolferth, 1932;Messer et al, 1951;Julian and Davies, 1957;Mounsey, 1953;Wells, 1954;Kelly, 1955;Bayer et al, 1956;Steinzeig et al, 1957;Wells, 1957;Di Perri and Fabrizi, 1958;Proctor et al, 1958;Donnelly et al, 1959;Rich, 1959;Muiesan et al, 1960). However, this measurement can only be obtained in patients in whom an opening snap is present.…”

“…Since the report in 1932 by Margolies and Wolferth on the opening snap in mitral stenosis, attempts have been made to evaluate this lesion by phonocardiography (Messer et al, 1951;Mounsey, 1953;Wells, 1954;Kelly, 1955;Bayer, Loogen, and Wolter, 1956;Craige, 1957;Julian and Davies, 1957;Steinzeig, et al, 1957;Wells, 1957;Di Perri and Fabrizi, 1958;Proctor et al, 1958;Donnelly, Maha, and Orgain, 1959;Leo and Hultgren, 1959;Rich, 1959;Dack et al, 1960;Muiesan et al, 1960;Nixon, Wooler, and Radigan, 1960;Di Bartolo, Nuniez-Dey, and Bendezu'-Prieto, 1962). The 2-OS interval measured from the aortic component of the second heart sound to the opening snap has been used for evaluation of the degree of severity of the stenotic lesion.…”

“…The 2-OS interval measured from the aortic component of the second heart sound to the opening snap has been used for evaluation of the degree of severity of the stenotic lesion. It is generally felt that as the severity of mitral stenosis increases, the 2-OS interval decreases (Kelly, 1955;Bayer et al, 1956;Steinzeig et al, 1957;Proctor et al, 1958;Donnelly et al, 1959;Rich, 1959;Di Bartolo et al, 1962). Therefore, the 2-OS interval has been frequently cited in the clinical evaluation of mitral valvular disease.…”

Q-1 or C-1 interval in the diagnosis of mitral stenosis.

“…Similar results were obtained by Proctor et al (1958). As is known, the duration of the Q-1 interval in mitral stenosis is inversely proportional to the length of the preceding cardiac cycle (Wells, 1957;Steinzeig et al, 1957;Di Perri and Fabrizi, 1958;Tavel, Feigenbaum, and Campbell, 1965b). Beo cause of this, the Q-1 intervals measured were o corrected to a standard heart rate of 75/min.°0 (R-R=800 msec.)…”

Observations on the Delayed First Heart Sound in Mitral Stenosis and Hypertension

“…With the advent of valvular surgery and the consequent need for more accurate assessment of mitral stenosis, interest in this observation has been renewed. [2][3][4][5][6][7][8] The measurement of the Q-1 interval, that is the interval between the onset of ventricular depolarization and the first heart sound has been accordingly evaluated as an index of the severity of stenosis. Recent observations in this laboratory have suggested that, in addition, the timing of the first heart sound may be altered in patients with hypertensive vascular disease."…”