Phleum pratense molecular pattern across Italy

Ciprandi, Giorgio; Scala, Enrico; Ariano, R

doi:10.23822/eurannaci.1764-1489.01

Cited by 11 publications

(12 citation statements)

References 14 publications

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“…However, a recent Italian study performed in 11 235 adult patients with AR showed percentages of IgE sensitization to P. pratense molecules comparable with our data …”

Section: Discussionsupporting

confidence: 92%

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules

Cipriani

Mastrorilli

Tripodi

et al. 2017

Allergy

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In a large pediatric population, the complexity of IgE sensitization profiles against P. pratense molecules is related to high atopic features although useless for predicting the clinical severity. The detection of serum IgE to Phl p 1, Phl p 7, and Phl p 12 can be used as clinical biomarkers of SARg and comorbidities. Further studies in different areas are required to test the impact of different IgE molecular profiles on AIT response.

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“…However, a recent Italian study performed in 11 235 adult patients with AR showed percentages of IgE sensitization to P. pratense molecules comparable with our data …”

Section: Discussionsupporting

confidence: 92%

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules

Cipriani

Mastrorilli

Tripodi

et al. 2017

Allergy

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“…(25%), birch (23.4%), dog (21%), Alternaria (20%), cypress (16%), Parietaria (16%), and Compositae (15%). There were geographical differences concerning the distribution of specific sensitizations consistently with previous studies (12)(13)(14). Nevertheless, there was no significant difference in terms of treatments and disease severity among the centers.…”

Section: F O R P U B L I C a T I O Nsupporting

confidence: 86%

The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world “ControL’Asma” study

Tosca

Marseglia

Ciprandi

et al. 2021

Eur Ann Allergy Clin Immunol

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“…Overall, the most frequent cause of sensitization found in Italy was the cypress pollen in C and S (26), and the grass pollen in NE and NW (15). Only in the main Islands, the Bermuda grass (Cynodon dactylon) sensitization surpassed timothy grass pollen IgE recognition, thus suggesting differences in the plant distribution or of other local genetic and/or environmental-related factors affecting the IgE mediated response to the allergen.…”

Section: Plant Food Panallergensmentioning

confidence: 98%

“…A total of 6052 ISAC-positive adult individuals (53.3% female; mean age 33 ± 19 years) were recruited by the participating centers. Patients were subdivided according to the classification of terri-tion patterns can be demonstrated, by means of molecular diagnostic approaches, for grasses or tree pollen allergy in different regions of Spain (13,14) or Italy (15,16,17), thus representing possible loco-regional signatures of sensitization. This has also been demonstrated in other countries, such as Africa and Asia (18,19,20).…”

Section: Study Cohortmentioning

confidence: 99%

An atlas of IgE sensitization patterns in different Italian areas. A multicenter, cross-sectional study

Scala

Villalta

Uasuf

et al. 2018

Eur Ann Allergy Clin Immunol

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The development of recombinant technology supported the allergy diagnostic work-up in the daily clinical practice, representing a useful tool for epidemiological studies. An atlas of the IgE sensitization profiles found throughout Italy was prepared from a nationwide, multicenter, cross-sectional study. 6052 unselected consecutive individuals, belonging to North-West [NW], North-East [NE], Centre [C], South [S], and Islands subset [Is] were evaluated by means of the ImmunoCAP ISAC test. The top-ranked sensitizations found were Cup a 1 in [C] (58.1%) and [S] (53.6%), Phl p 1 in the North (from 46.1% to 49%), and Cyn d 1 in [Is] (44.2%). High frequency of house dust mite group 2 molecules sensitization was found in [C] (36.9%) and [S] Italy (40.8%), whilst low level of reactivity was recorded in [NW] (20%). Pellitory hypersensitivity was mainly found in [C], [S], and [Is], whilst ragweed Amb a 1 sensitivity was particularly found in [NW] Italy. IgE recognition of PR-10, Profilin, and nsLTP was mutually exclusive in 69.1% of cases, PR-10 reactivity mostly occurring in [NE], Profilin in [NW], and nsLTP molecules recognition mainly recorded in [C] and [S]. Divergent IgE sensitization patterns were found along Italy, possibly linked to the distinct geographical locations, indicating multiplex system IgE analysis as a reliable approach for epidemiological evaluation even in small geographical areas.

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Phleum pratense molecular pattern across Italy

Cited by 11 publications

References 14 publications

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules

The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world “ControL’Asma” study

An atlas of IgE sensitization patterns in different Italian areas. A multicenter, cross-sectional study

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