Phlegmonous enteritis: a cause for acute abdomen with unusual findings

Post-endoscopic submucosal dissection phlegmonous enteritis: A case report and literature review

“…The etiology and pathogenesis of phlegmonous enteritis remain uncertain in academic literature. While the association between phlegmonous enteritis and different liver diseases is infrequently documented, it is sufficiently substantiated by several studies [ 8 , 9 , [11] , [12] , [13] , [14] , 17 , 18 ]. Additional uncommon predisposing factors include autoimmune disease (AID) [ 19 ], colon carcinoma [ 10 , 20 ], congestive heart failure (CHF) [ 20 ], and diabetes mellitus [ 9 , 13 ], among others.…”

“…Gastrointestinal phlegmon is an infrequent yet potentially fatal ailment that typically presents with acute abdominal pain and elevated body temperature [ [9] , [10] , [11] ]. The pathological characteristics encompass widespread purulent inflammation, primarily affecting the submucosal layer [ 8 , [11] , [12] , [13] , [14] ]. The inflammatory process may extend to the serosal surface, leading to the development of peritonitis and sepsis, which are challenging to diagnose without the use of laparotomy or postmortem examination [ 8 , [11] , [12] , [13] , [14] , [15] ].…”

“…The pathological characteristics encompass widespread purulent inflammation, primarily affecting the submucosal layer [ 8 , [11] , [12] , [13] , [14] ]. The inflammatory process may extend to the serosal surface, leading to the development of peritonitis and sepsis, which are challenging to diagnose without the use of laparotomy or postmortem examination [ 8 , [11] , [12] , [13] , [14] , [15] ]. The initial description of phlegmonous enteritis was provided by Rokitansky et al, in 1842 [ 16 ].…”

“…Phlegmonous enteritis, a rare yet potentially lethal condition resulting from pyogenic bacterial infections [ 8 ], can lead to hematogenous dissemination, triggering bacteremia and sepsis. This study presents the inaugural case of phlegmonous enteritis as a secondary consequence of ESD.…”