Philip Seeman's contributions to the story of schizophrenia

Abstract

Philip Seeman's isolation of the dopamine D2 receptor is an example of a small step that can lead to major change in the way that we conceptualize the etiology of schizophrenia.

How identity is produced and experienced in the context of mandated community‐based mental health care: An application of the theories of Grosz and Foucault

“…She goes on to explore how within this dis-enfranchised culture "being crazy is the worst possible identity you can assume" (p. 160), synonymous with being "isolated, disliked, unreachable" (p. 162). She points out the cultural trend in psychiatry to favor biological over psycho-social causation for mental disorders, theorizing that this is partially a backlash from the theory of the schizophrenogenic mother which caused unnecessary and unhelpful distress to families (Luhrmann, 2007;Seeman, 2002;Slipp, 1973). However, by linking the identity of "crazy"-a mental health label that people necessarily assumed in their quest for adequate services-to the theory of social defeat, Luhrmann forces us to reflect on not only how difficult social experiences can lead to psychotic disorders, but how cultural and systemic responses to mental illness can influence the course and outcome of the disease.…”

A Homogeneous Colorimetric Strategy Based on Rose-like CuS@Prussian Blue/Pt for Detection of Dopamine

“…DA is an important and abundant monoamine neurotransmitter that is closely connected to many neuronal activities, such as cognitive function [2], motor control [3], and memory function [4]. In particular, the pathophysiology of several psychiatric and neurological conditions, including Parkinson's disease [3], Huntington's disease [5], food and drug addiction [6], and schizophrenia [7], is intimately linked to aberrant DA secretion. Parkinson's disease is the second most common neurodegenerative disease; however, the early pathophysiological events and sequences of its dysfunction remain unknown.…”