Pheonolic Compounds from the Fruits of Viburnum sargentii Koehne

Abstract

Seven phenolic compounds were isolated from the fruits of Viburnum sargentii Koehne by silica gel column chromatography and preparative HPLC. On the grounds of chemical and spectroscopic methods, their structures were identified as (−)-Epicatechin (1),, quercetin-3-O-rutinoside (7). Compounds 5 and 6 are new monoterpene phenolic glycosides, compounds 1, 3 and 4 were isolated from the Viburnum genus for the first time, and compounds 2 and 7 from the Viburnum sargentii Koehne for the first time. Compounds 1-7 were also assayed for their antioxidant activities with DPPH free radicals.

Viburnum mullaha D. DON fruit (Indian cranberry): A potential source of polyphenol with rich antioxidant, anti-elastase, anti-collagenase, and anti-tyrosinase activities

“…polyphenolic contents have been analyzed in berries of other species of Viburnum including V. dilatatum, V. opulus, and V. sargentii. [27,32,[44][45][46][47] Kim et al [32] reported phenolic composition of squeezed fruit juice extracts of Viburnum dilatatum by employing NMR and liquid chromatography/MS techniques. The phenolic compounds included cyanidin 3-sambubioside, cyanidin 3-glucoside, 5-O-caffeoyl-4-methoxyl quinic acid, quercetin, and chlorogenic acid.…”

“…Kraujalyte et al [27] reported presence of nine phenolic compounds (chlorogenic acid, neochlorogenic acid, quinic acid, catechin, epicatechin, procyanidin C1, and three other unidentified compounds) in V. opulus juice by using ultra high performance liquid chromatography coupled to quadruple and time-of-flight mass spectrometry (UPLC-QTOF-MS). Xie et al [47] isolated seven phenolic compounds from the fruits of…”

“…sargentii Koehne by silica gel column chromatography and preparative HPLC. The phenolic compounds were identified as (−)-epicatechin 5,7,4′-trihydroxy-flavonoid-8-C-β-D-glucopyranoside, 1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-α-Lrhamnopyranoxypropyl)-2-methoxyphenoxy]-1,3-propane-diol (erythro), 1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-α-L-rhamnopyranoxypropyl)-2-methoxyphenoxy]-1,3-propanediol(threo), (R)-4-hydroxylphenol O-(6-O-oleuropeoyl)-β-D-glucopyranoside, (R)-3-methoxy-4-hydroxylphenol O-(6-Ooleuropeoyl)-β-D-glucopyranoside, quercetin-3-O-rutinoside [47].…”

Flavonoid Glycosides and Their Derivatives from the Herbs of Scorzonera austriaca Wild

“…The five known compounds were identified as 5,7,4′-trihydroxyflavone 6-C- [14], quercetin 3-O-rutinoside (3) [15], 5,7,4′-trihy …”

“…The five known compounds were identified as 5,7, [14], quercetin 3-O-rutinoside (3) [15], 5,7,4 1 -trihy droxyflavone 6-C-β-D -glucopyranoside (4) [16], and 3 1 -methoxy-5,7,4 1 -trihydroxyflavone 6-C-β-D-glucopyranoside (5) [17], by comparison of various data with the reported compounds. , and 113.6 (CH) were deduced to arise from a trans-caffeoyl moiety based on the analysis of 1 H-1 H COSY, HMQC, and HMBC of 6 and the comparison of 1 H-and 13 C-NMR spectra of 6 with the reported values [18].…”