Phenyl Esters

Electrochemical synthesis and crystal structure studies of defective dicubane tetranuclear hydroxo and carboxamide ligand bridged cobalt(II)–cobalt(III) complexes with carboxamides produced from unprotected hydroxyaromatic carboxylic acids

“…Only a very approximate structure model could be worked out with these data. It confirmed the presence of the expected [Co 4 (m 3 -OH) 2 (m 2 -Me 2 hyneb) 2 (CH 3 CN) 6 ] complex analogous to 1 in 1Á2H 2 OÁ2CH 3 CN, but the complexes formed a very open structure with big pores extending along [001] and large layer-like spaces parallel to (001) that were obviously filled with many disordered acetonitrile solvent molecules, making the solid unstable due to desolvation. …”

“…Dark cuboidal crystals up to 1 mm in size of the product were obtained after 1 week. Satisfactory elemental analysis could not be obtained due to instant desolvation; however, an approximate crystal structure model obtained from weak X-ray single-crystal diffraction data (vide infra) confirmed the presence of the expected [Co 4 (m 3 -OH) 2 (m 2 -Me 2 hyneb) 2 (CH 3 CN) 6 ] complex analogous to 1. The analytical data for a solvate species, similar to that of complex 1, that is [Co 4 (m 3 -OH) 2 (m 2 -Me 2 hyneb) 2 …”

“…Conventional methods for the synthesis of amides involve the treatment of activated derivatives of acids with the corresponding amine. Phenyl esters of salicylic acid have been effectively used for the synthesis of 2-hydroxybenzamides [5]; however, their synthesis from salicylic acids requires harsh conditions [6]. The synthesis of 2-hydroxynaphthamides has been carried out by various methods [7][8][9][10], including one starting from 2-hydroxy-3-naphthoic acid and using halogenating agents such as PCl 3 [11], and SOCl 2 [12].…”

Linker-modified quinoline derivatives targeting HIV-1 integrase: synthesis and biological activity

“…Esterification of the carboxylic acid function of 2a was investigated first. Treatment of the latter compound with n-butanol at 100°C in the presence of polyphosphoric acid (PPA) 5 gave the n-butyl ester 2b with a 80% yield. However, the use of the strongly basic conditions required for the cleavage of this ester at the final stage having resulted in the destruction of target molecules, this protecting group was not suited to the task.…”

Complete esterification of ethylene–methacrylic acid and ethylene–acrylic acid copolymers by reaction of their salts with ethyl iodide

“…H2S04,' BF3 * OEt2,4 polyphosphoric acid, 21 and polystyrene sulfonic acidg instead of p-toluene sulfonic acid" under reflux and azeotoropic distillation for 35 h. The results showed that any acid catalyst in the reaction did not give more than 99.0 mol % conversion and a drastic change of the reaction time.…”