Phenotypic Responses to and Genetic Architecture of Sterility Following Exposure to Sub-Lethal Temperature During Development

Zwoinska, Martyna K.; Rodrigues, Leonor R.; Slate, Jon; Snook, Rhonda R.

doi:10.3389/fgene.2020.00573

Cited by 29 publications

(41 citation statements)

References 86 publications

(118 reference statements)

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“…Furthermore, there is evidence for sex-specific effects of temperature on fertility with potential implications for operational sex ratios. In D. melanogaster , increased developmental temperatures negatively affect male fertility, but females are much less sensitive to this treatment ( Zwoinska et al 2020 ), suggesting temperature changes may modify operational sex ratio in this species. In mice, heat stress can cause a decrease in sperm viability with a differential effect on Y- and X-bearing sperm, potentially affecting offspring sex ratio ( Pérez-Crespo et al 2008 ).…”

Section: Effects Of Environmental Change On Sexual Selectionmentioning

confidence: 99%

Editorial: Sexual selection and environmental change: what do we know and what comes next?

Pilakouta

Ålund

2021

Current Zoology

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Section: Effects Of Environmental Change On Sexual Selectionmentioning

confidence: 99%

Editorial: Sexual selection and environmental change: what do we know and what comes next?

Pilakouta

Ålund

2021

Current Zoology

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“…Assuming that enough generations have passed as to exhibit divergent selection to thermal changes, genome-wide association (GWAS) ( Hirschhorn and Daly, 2005 ) and selection (GWSS) ( Sabeti et al, 2007 ) scans ( Figure 1D ) are essential analytical tools to reconstruct the genomic architecture of adaptive trait divergence to thermal stress ( Lecheta et al, 2020 ; Zwoinska et al, 2020 ). These methods assume that some allele variants are in linkage disequilibrium (LD) ( Slatkin, 2008 ) with causal variants that influence the adaptive phenotype ( Morris and Borevitz, 2011 ; Tam et al, 2019 ), a.k.a.…”

Section: From Deeper Genomic Signatures Of Selection To Mid-term Predmentioning

confidence: 99%

Predicting Thermal Adaptation by Looking Into Populations’ Genomic Past

2020

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Molecular evolution offers an insightful theory to interpret the genomic consequences of thermal adaptation to previous events of climate change beyond range shifts. However, disentangling often mixed footprints of selective and demographic processes from those due to lineage sorting, recombination rate variation, and genomic constrains is not trivial. Therefore, here we condense current and historical population genomic tools to study thermal adaptation and outline key developments (genomic prediction, machine learning) that might assist their utilization for improving forecasts of populations’ responses to thermal variation. We start by summarizing how recent thermal-driven selective and demographic responses can be inferred by coalescent methods and in turn how quantitative genetic theory offers suitable multi-trait predictions over a few generations via the breeder’s equation. We later assume that enough generations have passed as to display genomic signatures of divergent selection to thermal variation and describe how these footprints can be reconstructed using genome-wide association and selection scans or, alternatively, may be used for forward prediction over multiple generations under an infinitesimal genomic prediction model. Finally, we move deeper in time to comprehend the genomic consequences of thermal shifts at an evolutionary time scale by relying on phylogeographic approaches that allow for reticulate evolution and ecological parapatric speciation, and end by envisioning the potential of modern machine learning techniques to better inform long-term predictions. We conclude that foreseeing future thermal adaptive responses requires bridging the multiple spatial scales of historical and predictive environmental change research under modern cohesive approaches such as genomic prediction and machine learning frameworks.

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“…However, recently there has been renewed interest in the consequences of sub‐lethal developmental temperature on fertility. Elevated temperatures experienced during development have been shown to reduce both male and female fertility, placing populations at greater risk of extinction in the face of global climate change (David et al ., 2005; Colinet et al, 2015; Sage et al ., 2015; Sales et al ., 2018; Walsh et al ., 2019; Parratt et al ., 2020; Zwoinska et al ., 2020).…”

Section: Introductionmentioning

confidence: 99%

Age‐specific sensitivity of sperm length and testes size to developmental temperature in the bruchid beetle

2021

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In an era of global warming, the negative effects of temperature stress on fertility could intensify predicted losses of biodiversity. Male fertility is particularly sensitive to temperature stress, yet we have an incomplete understanding of when, during reproductive ontogeny, spermatogenesis is most affected. Here, we used a temperature-switch protocol to identify when during development temperature affects the expression of sperm length and testes size in the bruchid beetle Callosobruchus maculatus. Egg-to-adult development took place at 17°C, 27°C or 33°C for either the full duration of pre-imago development or it was switched at different stages during development. Full development at 17°C or 33°C resulted in significantly shorter sperm than at 27°C. However, when developing larvae were switched to higher or lower temperatures, we observed switch-specific phenotypic expression of sperm length and testes size. Our key finding was that sperm length was sensitive to high-temperature stress during the early stages of ontogeny and to low-temperature stress during the latter stages of ontogeny. Such age-specific developmental sensitivity suggests that infertility resulting from transient heat stress (i.e. heatwaves) could be mitigated by age-related developmental heterogeneity within populations. Those individuals able to avoid severe effects of heat stress on fertility, through serendipitously being at less-sensitive stages of development, could potentially compensate for the loss of fertility experienced by those individuals at more sensitive stages of development.

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Phenotypic Responses to and Genetic Architecture of Sterility Following Exposure to Sub-Lethal Temperature During Development

Cited by 29 publications

References 86 publications

Editorial: Sexual selection and environmental change: what do we know and what comes next?

Editorial: Sexual selection and environmental change: what do we know and what comes next?

Predicting Thermal Adaptation by Looking Into Populations’ Genomic Past

Age‐specific sensitivity of sperm length and testes size to developmental temperature in the bruchid beetle

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