Phenotypic Heterogeneity of Asian Indian Inversion Deletions Gγ(Aγδβ)0 Breakpoint A and Breakpoint B

Contrasting co-inheritance of alpha and beta mutations in delta beta thalassemia and hereditary persistence of fetal hemoglobin: a study from India

“…Our results are quiet similar to above-mentioned studies [14,21,23]. One case report from our institute (AIIMS, New Delhi) in year 2012 showed coexistence of δβ thalassemia with α and β which is quiet rare and interesting finding [23].…”

A Compound Heterozygous Asian Indian Inversion Deletion Gγ(Aγδβ)0 with β-Thalassemia in Central India: A Case Report

“…C) mutation with (db) 0 thalassemia influences the upregulation of c gene. Similar findings are reported by Dehury et al [6] and Pandey et al [7]. However, in case of compound heterozygotes reported by Pandey et al [7] both Hb A2 and HB F were significantly lower than in the present case.…”

“…Similar findings are reported by Dehury et al [6] and Pandey et al [7]. However, in case of compound heterozygotes reported by Pandey et al [7] both Hb A2 and HB F were significantly lower than in the present case. Our report is comparable to the report of Dehury et al [6].…”

Compound heterozygous state of β-thalassemia with IVS1-5 (G→C) mutation and Indian deletion-inversion Gγ(Aγδβ)0-thalassemia in eastern India

“… 10 Recently, Pandey et al described seven cases with Indian deletion-inversion Gγ(Aγδβ) 0 -thalassemia, of which three cases were co-inherited with β-thalassemia with the IVS1-5(G→C) mutation. 11 These three cases had low values of both Hb A 2 (3.2%, 2.8%, and 2.7%) and Hb F (21.3%, 10.7% and 20.3%) compared to the 6.9% and 84.6% of Hb A 2 and Hb F, respectively in the current case. Their three cases were transfusion dependent and showed moderate anemia.…”