Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation

McAulay, G.; Borgeat, Kieran; Sargent, Julia; Mõtsküla, Paul; Neves, J.; Dukes‐McEwan, Joanna; Fuentes, Virginia Luis

doi:10.1016/j.tvjl.2018.02.015

Cited by 2 publications

(3 citation statements)

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“…The left atrium, along with the pulmonary veins, assumes a central role in the initiation and perpetuation of AF in humans [ 34 ]. Left atrial enlargement serves as a readily identifiable manifestation of left atrial remodeling in response to cardiac disease, as elucidated in five articles within this systematic review [ 2 , 4 , 5 , 8 , 26 ]. The use of two-dimensional echocardiography facilitates the assessment of LAE through both the measurement of absolute LAD and the calculation of the LA:Ao ratio [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

“…The roles of heart rate and CHF in dogs with secondary AF are topics marked by controversy. Elevated heart rate is a prevalent finding in dogs with cardiac disease and AF, as it is often associated with increased sympathetic tone, a pathophysiological consequence of advanced cardiac disorders [ 4 , 5 , 26 , 28 , 31 ]. However, the persistent elevation in heart rate linked to AF can potentially contribute to tachycardia-induced cardiomyopathy [ 2 , 49 ].…”

Section: Discussionmentioning

confidence: 99%

“…An elevated heart rate is commonly observed as a clinical hallmark in individuals with AF [ 3 , 11 ]. In the context of this systematic review, two papers [ 26 , 28 ] highlighted an elevated heart rate at presentation as a risk factor for the development of AF. One of these studies reported an OR of 1.123, shedding light on the potential significance of heart rate in predicting AF development [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

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Risk Factors for Atrial Fibrillation in the Dog: A Systematic Review

Arcuri,

Valente,

Perini

et al. 2024

Veterinary Sciences

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Different risk factors for atrial fibrillation (AF) development have been identified in numerous studies on humans, but this information is less clearly available on the dog. The aim of this systematic review is to determine the risk factors for AF in the dog. Following the PRISMA 2020 guidelines, we conducted a comprehensive search using the Web of Science and Scopus databases for articles reporting on cases of spontaneously occurring AF in dogs. The level of evidence was assessed using the Evidence Quality Grading System of the National Institute of Health. One thousand forty-three studies were initially identified, and twenty of them were included in this systematic review involving 2,359,275 dogs, of which 4807 showed spontaneously occurring AF. Genetics, for the Irish Wolfhound, increased body weight, and left atrial enlargement were the main risk factors for the development of AF in dogs with different cardiac diseases, particularly myxomatous mitral valve disease (MMVD) and dilated cardiomyopathy (DCM). However, some differences were found between these two cardiac diseases regarding additional risk factors. In particular, the presence of congestive heart failure and echocardiographic evidence of increased left atrial pressure or the presence of right atrial enlargement emerged as risk factors in dogs with MMVD or DCM, respectively. Furthermore, significant differences in risk factors were observed between dogs and humans. In particular, advanced age and male sex are not reliable indicators of an increased risk of AF in dogs.

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