Phenotypic and Genotypic Characterization of Clinical EnterotoxigenicEscherichia coliIsolates from Shenzhen, China

Abstract

ETEC isolates in Shenzhen of China appeared highly diverse, yet some isolates belonged to well-defined clonal groups sharing a unique set of virulence factors, serotypes, and MLST sequence types. Facing the challenge of ETEC antigenic diversity and geographic variation, novel molecules and/or classical antigens designed by novel strategies might contribute to ETEC vaccine development.

Identification of common virulence factors present in enterotoxigenicEscherichia coliisolated from diarrhoeal patients in Kolkata, India

“…ST is higher than LT in Shenzhen, China (Li et al . ). In our community based comparator strains, we found that the pattern is reverse i.e., ST+LT was the least prevalent toxin and LT was the predominant one.…”

“…; Li et al . ). It has also been identified in some study as one of the predominant CF responsible for traveller's diarrhoea (Rivera et al .…”

“…Similarly, 46% samples were CFs negative for isolates from Shenzhen, China (Li et al . ). In ETEC isolated from travellers 31% of all strains did not possess any of the tested CFs (Rivera et al .…”

“…) and Shenzhen, China (Li et al . ). Though ETEC was mainly associated with children less than 5 years of age but it also affects the adults which are too considered for studies related to ETEC.…”

A new plasmid carrying mphA causes prevalence of azithromycin resistance in enterotoxigenic Escherichia coli serogroup O6

“…serogroups in ETEC, is the dominant serogroup of ETEC in China. Moreover, it has shown an upward trend in recent years [4][5][6].…”