Phenotypic and Functional Responses of Human Decidua Basalis Mesenchymal Stem/Stromal Cells to Lipopolysaccharide of Gram-Negative Bacteria

Alshareef, Ghofran Hasan; Mohammed, Afrah E.; Abumaree, Mohamed; Basmaeil, Yasser

doi:10.2147/sccaa.s332952

Cited by 2 publications

(1 citation statement)

References 114 publications

(193 reference statements)

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“…It also seems that DSCs have a higher potential for fighting inflammation in inflammatory environments, as their location and activity is in such an environment with higher oxidative stress and inflammatory mediators. Therefore, stromal cells from placenta are more suitable candidates for the treatment of various inflammatory disorders [ 97 ] .…”

Section: Cell-based Therapies Of Noa By Paracrine and Anti-inflammato...mentioning

confidence: 99%

Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia

et al. 2022

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The rate of infertility has globally increased in recent years for a variety of reasons. One of the main causes of infertility in men is azoospermia that is defined by the absence of sperm in the ejaculate and classified into two categories: obstructive azoospermia and non-obstructive azoospermia. In non-obstructive azoospermia, genital ducts are not obstructed, but the testicles do not produce sperm at all, due to various reasons. Non-obstructive azoospermia in most cases has no therapeutic options other than assisted reproductive techniques, which in most cases require sperm donors. Here we discuss cell-based therapy approaches to restore fertility in men with non-obstructive azoospermia including cell-based therapies of non-obstructive azoospermia using regenerative medicine and cell-based therapies of non-obstructive azoospermia by paracrine and anti-inflammatory pathway, technical and ethical challenges for using different cell sources and alternative options will be described, and then the more effectual approaches will be mentioned as future trends.

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Section: Cell-based Therapies Of Noa By Paracrine and Anti-inflammato...mentioning

confidence: 99%

Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia

et al. 2022

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Applications of extraembryonic tissue-derived cells in vascular tissue regeneration

Goushki,

Kharat,

Kehtari

et al. 2024

Stem Cell Res Ther

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Vascular tissue engineering is a promising approach for regenerating damaged blood vessels and developing new therapeutic approaches for heart disease treatment. To date, different sources of cells have been recognized that offer assistance within the recovery of heart supply routes and veins with distinctive capacities and are compelling for heart regeneration. However, some challenges still remain that need to be overcome to establish the full potential application of these cells. In this paper, we review the different cell sources used for vascular tissue engineering, focusing on extraembryonic tissue-derived cells (ESCs), and elucidate their roles in cardiovascular disease. In addition, we highlight the intricate interplay between mechanical and biochemical factors in regulating mesenchymal stem cell (MSC) differentiation, offering insights into optimizing their application in vascular tissues.

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Phenotypic and Functional Responses of Human Decidua Basalis Mesenchymal Stem/Stromal Cells to Lipopolysaccharide of Gram-Negative Bacteria

Cited by 2 publications

References 114 publications

Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia

Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia

Applications of extraembryonic tissue-derived cells in vascular tissue regeneration

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