Phenolic sucrose esters: evolution, regulation, biosynthesis, and biological functions

Deng, Renyu; Li, Wei; Berhow, Mark A.; Jander, Georg; Zhou, Shaoqun

doi:10.1007/s11103-021-01142-y

Cited by 6 publications

(2 citation statements)

References 106 publications

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“…PSEs have been isolated from various species of medicinal plants in the families Arecaceae , Boraginaceae , Brassicaceae , Caryophyllaceae , Liliaceae , Melanthiaceae , Polygonaceae , Poaceae , Polygalaceae , Rutaceae , and Rosaceae . These compounds exhibit anti-inflammatory, antioxidant, hypoglycaemic, and anticancer activities ( Figure 24 ) 139–141 .…”

Section: Inhibitors Of Tyrosinasementioning

confidence: 99%

Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure–activity relationship

Gębalski

Graczyk

Załuski

2022

Journal of Enzyme Inhibition and Medicinal Chemistry

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Human has used plants to treat many civilisation diseases for thousands of years. Examples include reserpine (hypertension therapy), digoxin (myocardial diseases), vinblastine and vincristine (cancers), and opioids (palliative treatment). Plants are a rich source of natural metabolites with multiple biological activities, and the use of modern approaches and tools allowed finally for more effective bioprospecting. The new phytochemicals are hyaluronidase (Hyal) inhibitors, which could serve as anti-cancer drugs, male contraceptives, and an antidote against venoms. In turn, tyrosinase inhibitors can be used in cosmetics/pharmaceuticals as whitening agents and to treat skin pigmentation disorders. However, the activity of these inhibitors is stricte dependent on their structure and the presence of the chemical groups, e.g. carbonyl or hydroxyl. This review aims to provide comprehensive and in-depth evidence related to the anti-tyrosinase and anti-Hyal activity of phytochemicals as well as confirming their efficiency and future perspectives.

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Section: Inhibitors Of Tyrosinasementioning

confidence: 99%

Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure–activity relationship

Gębalski

Graczyk

Załuski

2022

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…Highlights include the power of such approaches in the backdrop of exponentially increasing multi-omics data, especially in many intractable non-model species. A review by Deng et al (2021) showcases the application of phylogenetic reconstructions for the independent evolution of phenolic sucrose esters in monocots and dicots. While more detailed studies are needed to understand their biological functions, the inducibility of those compounds through pathogens and stress-related phytohormones strongly imply their involvement in defense.…”

mentioning

confidence: 99%

Molecular biology of chemical defenses

Koo

Arimura

2022

Plant Mol Biol

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Structurally diverse specialized metabolites of maize and their extensive biological functions

Zhou

Jin

et al. 2023

Journal Cellular Physiology

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Maize originated in southern Mexico and various hybrid varieties have been bred during domestication. All maize tissues are rich in specialized plant metabolites (SPMs), which allow the plants to resist the stresses of herbivores and pathogens or environmental factors. To date, a total of 95 terpenoids, 91 phenolics, 31 alkaloids, and 6 other types of compounds have been identified from maize. Certain volatile sesquiterpenes released by maize plants attract the natural enemies of maize herbivores and provide an indirect defensive function. Kauralexins and dolabralexins are the most abundant diterpenoids in maize and are known to regulate and stabilize the maize rhizosphere microbial community. Benzoxazinoids and benzoxazolinones are the main alkaloids in maize and are found in maize plants at the highest concentrations at the seedling stage. These two kinds of alkaloids directly resist herbivory and pathogenic infection. Phenolics enhance the cross‐links between maize cell walls. Meanwhile, SPMs also regulate plant–plant relationships. In conclusion, SPMs in maize show a large diversity of chemical structures and broad‐spectrum biological activities. We use these to provide ideas and information to enable the improvement of maize resistances through breeding and to promote the rapid development of the maize industry.

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Phenolic sucrose esters: evolution, regulation, biosynthesis, and biological functions

Cited by 6 publications

References 106 publications

Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure–activity relationship

Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure–activity relationship

Molecular biology of chemical defenses

Structurally diverse specialized metabolites of maize and their extensive biological functions

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