Phenolic compounds from the rhizome of Renealmia nicolaioides Loes.: a new diarylheptanoid

Abstract

How to cite: GeVÚ KV, CARVAlhO mG, SIlVA IG, lImA hRP, CASTRO RN AND DA CUNhA m. 2019. Phenolic compounds from the rhizome of Renealmia nicolaioides loes.: a new diarylheptanoid. An Acad Bras Cienc 91: e20180312.Abstract: This study aims to identify phenolic compounds in dichloromethane and methanolic extracts of the rhizome of Renealmia nicolaioides collected in the North Region of Brazil. Two known diarylheptanoids, 1,7-bis(4-hydroxyphenyl)-(1e)-1-hepten-3-one (1), and 5R-1,7-bis(4-hydroxyphenyl)-1e-hepten-5-ol (2), and a new one (1R,2S,5S)-2-hydroxy-1,7(p-hydroxyphenyl)-centrolobine (3), as well as one flavonoid, 3-metoxi-quercetin (4) were isolated by chromatographic procedure and identified by spectroscopic techniques (1h and13C NmR, hRmS and CD). The acetyl derivative of 2 was used to confirm its structure. All four compounds are reported for the first time for this genus, and this is the first occurrence of compound 1 as a natural metabolite. The results reported here are unprecedented for the genus Renealmia.

Evaluation of Phenolic Compounds in Rhizomes of Three Renealmia L. f. Species: Quantification, Antioxidant Activity and Histolocalization

“…Diarylheptanoids, 1,7bis(4-hydroxyphenyl)-(1E)-1-hepten-3-one, 5R-1,7-bis(4-hydroxyphenyl)-1E-hepten-5-ol and (1R,2S,5S)-2-hydroxy-1,7(phydroxyphenyl)-centrolobine, as well as one flavonoid, 3-metoxi-quercetin, have been recently isolated from R. nicolaioides rhizome extracts. 32 The flavonoid (flavones and flavonols) content was low in the three extracts and corresponded to 3.12-15.63 % of the TP. These results may be related to the diversity of flavonoid types (chalcones, flavanones, flavones, flavones, catechins) found in Renealmia species, as well as the tendency for rhizomes to accumulate diarylheptanoids, another class of phenolic compounds.…”

“…These results may be related to the diversity of flavonoid types (chalcones, flavanones, flavones, flavones, catechins) found in Renealmia species, as well as the tendency for rhizomes to accumulate diarylheptanoids, another class of phenolic compounds. [32][33][34][35][36][37] Table 2 shows the results of the antioxidant activity of rhizome extracts from Renealmia species tested by three different methods, DPPH, FRAP and ABTS. We found a significant correlation between total phenolic content and the antioxidant activity in relation to FRAP and ABTS assays of the extracts (Table 3).…”