Phenolic Compounds and Antioxidant Activities of Eight Species of Fabaceae That Are Commonly Used in Traditional Medical Practices in the Republic of Suriname

Mans, Dennis R.A.; Friperson, Priscilla; Pawirodihardjo, Jennifer; Djotaroeno, Meryll

doi:10.5772/intechopen.106076

Cited by 3 publications

(1 citation statement)

References 198 publications

(299 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This secondary metabolite is used as a fragrance in both culinary and cosmetic products. Almost one thousand variants of this secondary metabolite have been isolated from more than eight hundred different species [ 245 ].…”

Section: Role Of Michael Acceptorsmentioning

confidence: 99%

Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2

Andrés,

Pérez de la Lastra,

Bustamante Munguira

et al. 2024

IJMS

View full text Add to dashboard Cite

The phrase “Let food be thy medicine…” means that food can be a form of medicine and medicine can be a form of food; in other words, that the diet we eat can have a significant impact on our health and well-being. Today, this phrase is gaining prominence as more and more scientific evidence suggests that one’s diet can help prevent and treat disease. A diet rich in fruits, vegetables, whole grains, and lean protein can help reduce the risk of heart disease, cancer, diabetes, and other health problems and, on the other hand, a diet rich in processed foods, added sugars, and saturated fats can increase the risk of the same diseases. Electrophilic compounds in the diet can have a significant impact on our health, and they are molecules that covalently modify cysteine residues present in the thiol-rich Keap1 protein. These compounds bind to Keap1 and activate NRF2, which promotes its translocation to the nucleus and its binding to DNA in the ARE region, triggering the antioxidant response and protecting against oxidative stress. These compounds include polyphenols and flavonoids that are nucleophilic but are converted to electrophilic quinones by metabolic enzymes such as polyphenol oxidases (PPOs) and sulfur compounds present in foods such as the Brassica genus (broccoli, cauliflower, cabbage, Brussel sprouts, etc.) and garlic. This review summarizes our current knowledge on this subject.

show abstract

Section: Role Of Michael Acceptorsmentioning

confidence: 99%

Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2

Andrés,

Pérez de la Lastra,

Bustamante Munguira

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

Herbal Extracts in Orofacial Pain: Systematic Review, Direct and Indirect Meta-analysis

Barrera,

Cepeda,

Báez

et al. 2024

Preprint

View full text Add to dashboard Cite

There is limited knowledge regarding the efficacy of the use of herbal extracts in orofacial pain. A systematic review and a meta-analysis of randomized controlled trials, to assess the analgesic effect of herbal extracts on pain intensity in various painful orofacial conditions was conducted. Sixty-two studies were included. The intervention treatment consisted in the use of herbal extracts compared with placebo and/or standard treatment. The primary outcome was pain intensity assessed before and after the intervention, using any pain scale from 0 to 10. Pain scores were compared with baseline scores in each treatment. When compared with standard therapy, the pooled results of the patients who received herbal extracts reported lower pain intensity; in periodontal pain (mean difference [MD] = -0.92, 95% confidence interval [-6.69, 4.85]), oral surgery pain (MD = 18.80 [8.80, 28.79]), oral neuropathic pain (MD = 20.34 [6.16, 34.52]), endodontic pain (MD = -8.04 [-11.72, -4.37]), oral mucosal pain (MD = 8.74 [2.76, 14.73]), and temporomandibular pain (MD = 30.94 [6.04, 55.83]). The findings indicate a pain-attenuating effect of herbal extracts such as Cannabis, Turmeric, Capsaicin, Licorice, Ginger, Chamomile, Clove, Hypericum perforatum, Arnica montana, Aloe vera and Calendula use in oral surgery pain, oral neuropathic pain, oral mucosal pain, and temporomandibular pain. The findings of this study indicate that herbal extracts may provide a valuable alternative to traditional pain medication. Additionally, it may also be a promising source for developing new active ingredients for pharmaceuticals.

show abstract

Ethnobotanical study of medicinal plants used by the people of Mosop, Nandi County in Kenya

Maiyo,

Njeru,

Toroitich

et al. 2024

Front. Pharmacol.

View full text Add to dashboard Cite

Background: Throughout the history, nature has provided mankind with most of their basic needs, which include food, shelter, medicine, clothes, flavours, scents as well as raw materials. Given that they are an integral part of cultural heritage, medicinal plants have played a significant role in human healthcare systems around the world. Investigating various biological resources for use as medicines requires ethnomedicinal studies.Methods: Data on utilization of ethnomedicinal plants from local healers in Kenya’s Mosop Sub-County in Nandi County was documented through open-ended, semi-structured questionnaires. A number of quantitative indices, such as the Use Citation (UC), Informant Consensus Factor (ICF), Use Value (UV), Frequency of Citation (FoC) and Relative Frequency of Citation (RFC) were used to convey the potential medical benefits, vitality and variety of the ethnomedicine.Results: 102 informants provided information on 253 ethnomedicinal plant species, classified into 74 families. There were 249 native plant species identified, along with few exotic species: Senegalia senegal (L.) Britton, Persea americana Mill, Carica papaya L. and Solanum betaceum Cav. Of all recorded species, 32% and 27% were herbs and trees, respectively. Among plant parts, leaves were most frequently utilized (27%) and roots (26%), while decoctions (21%) were the most widely used formulations. The dominant family was Asteraceae, with 28 species, followed by Lamiaceae, with 19 species. The highest ICF value was 0.778 for a number of parasitic and infectious illnesses, including ringworms, athlete’s foot rot, tetanus, typhoid, intestinal parasites, abscesses, malaria, and amoebiasis. The study’s data validates the region’s widespread use of traditional medicinal plant remedies.Conclusion: The current study will lay a foundation of knowledge for future research investigations. The abundance of knowledge regarding ethnomedicinal species and their medicinal applications will stimulate further phytochemical and pharmacological research, which could lead to the discovery of potentially significant pharmaceuticals.

show abstract

Phenolic Compounds and Antioxidant Activities of Eight Species of Fabaceae That Are Commonly Used in Traditional Medical Practices in the Republic of Suriname

Cited by 3 publications

References 198 publications

Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2

Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2

Herbal Extracts in Orofacial Pain: Systematic Review, Direct and Indirect Meta-analysis

Ethnobotanical study of medicinal plants used by the people of Mosop, Nandi County in Kenya

Contact Info

Product

Resources

About