Phenolic Compound Profile by UPLC-MS/MS and Encapsulation with Chitosan of Spondias mombin L. Fruit Peel Extract from Cerrado Hotspot—Brazil

Abstract

Taperebá (Spondias mombin L.) is a native species of the Brazilian Cerrado that has shown important characteristics such as a significant phenolic compound content and biological activities. The present study aimed to characterize the phenolic compound profile and antioxidant activity in taperebá peel extract, as well as microencapsulating the extract with chitosan and evaluating the stability of the microparticles. The evaluation of the profile of phenolic compounds was carried out by UPLC-MS/MS. The in vitro antioxidant activity was evaluated by DPPH and ABTS methods. The microparticles were obtained by spray drying and were submitted to a stability study under different temperatures. In general, the results showed a significant content of polyphenols and antioxidant activity. The results of UPLC-MS/MS demonstrated a significant content of polyphenols in taperebá peel, highlighting the high content of ellagic acid and quercetin compounds. There was significant retention of phenolic compounds when microencapsulated, demonstrating high retention at all evaluated temperatures. This study is the first to microencapsulate the extract of taperebá peel, in addition to identifying and quantifying some compounds in this fruit.

Phytopharmacological Activities of Spondias mombinLinn: A Review

“…32 Quantification of various phenolic chemicals, including flavonols, phenylpropanoids, benzoic acid derivatives, coumarins, stilbenes, dihydrochalcones, flavones, and flavonones, was performed using ultrahigh performance liquid-chromatography-MS/MS (UPLC-MS/MS) on the fruit peel of S. mombin. 33 A total of fourteen flavonol substances were measured and determined. Quercetin was the predominant component, with myricetin and Kaempferol-3-Glc following in abundance.…”

“…Sinensetin and Luteolin-7-O-Glc were the most prominent flavones. 33 Pharmacological properties of S. mombin Linn S. mombin is of great ethnopharmacological relevance as virtually every component of the plant has shown useful therapeutic effects. Amongst its medicinal activities include:…”

Structural and Anticancer Studies of Methoxyflavone Derivative from Strychnos pseudoquina A.St.-Hil. (Loganiaceae) from Brazilian Cerrado

“…The Cerrado is the second largest biome in Brazil by area and the world’s richest savanna in terms of biodiversity. , Its high degree of endemism and the loss of its native area of approximately 46%, due to agricultural expansion processes, have made it one of the 34 hot spots for conservation in the world. , Among the species of native Cerrado plants, Strychnos pseudoquina stands out, popularly known as “quina-do-cerrado”. − Regarding phytochemical studies using S. pseudoquina, the presence of secondary metabolites such as alkaloids and flavonoids is normally demonstrated, and their occurrence is explained by soil conditions, frequent fires, and water stress existing in the Cerrado. ,− …”

“… 5 − 7 Regarding phytochemical studies using S. pseudoquina , the presence of secondary metabolites such as alkaloids and flavonoids is normally demonstrated, and their occurrence is explained by soil conditions, frequent fires, and water stress existing in the Cerrado. 4 , 8 − 12 …”