Phenolic compound profile, and evaluation of biological properties of Bassia muricata (L.) Asch. aerial part

Abstract

Current study verifies the biological efficiency of Bassia muricata (Chenopodiaceae vent), a wild plant in the Algerian desert. MeOH extract (70%) of the aerial parts of B. muricata was tested for antibacterial, anti-inflammatory and antioxidant activities. In addition to determining the value of the SPF and its effectiveness as hypoglycemia through a glucose uptake assay by yeast cells. Its phenolic content was also verified by quantitative estimations and RP-HPLC-UV analysis. MeOH extract of B. muricata exhibited antioxidant effects, where it showed good to moderate free radical inhibition activity towards both DPPH• and OH•, and this corresponded with excellent anti-hemolytic activity. As well as being a Fe2+ and molybdate reducing agent, the extract showed moderate photoprotective activity with SPFSpectrophootometric=18.89±0.005. It also has anti-inflammatory properties and enhances glucose uptake. MeOH extract of B. muricata showed remarkable antibacterial activity against B. subtilis, L. innocua, S. aureus, E. coli and P. aeruginosa. It did not give efficacy against S. typhimurium. Its phenolic content on the other hand was verified by quantitative estimations and RP-HPLC-UV analysis, which revealed the presence of chlorogenic acid, p-coumarin acid, gallic acid as a major phenolic compounds. These results showed that B. muricata could be useful as source of bioactive compounds for food, the pharmaceutical industry and the manufacture of cosmetics.

Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara

“…In terms of the quantities of individual phenolic acids and flavonoids, the content of chlorogenic acid in H. strobilaceum (85.77 µg/100 mg ED) was lower than that reported in Bassia muricata (288 µg/100 mg ED) by Gheraissa et al [34], while the content of p-Comuaric acid in S. fruticosa (1.63 µg/100 mg ED) was higher than that reported in Beta vulgaris L. root (0.74 µg/100 mg ED) by El-Beltagi et al [35]. On the other hand, the amount of rutin in S. fruticosa (367.56 µg/100 mg ED) was much higher than that reported in other plants of the Chenopodiaceae family, such as Bassia muricata (32 µg/100 mg ED) by Gheraissa et al [34] and Beta vulgaris L. root (not detected) by El-Beltagi et al [35].…”

“…Based on the comparison between Table 5 and previous studies (see Table S1), it can be observed that both H. strobilaceum and S. fruticosa contain significant amounts of phenolic acids and flavonoids, which is consistent with the findings of previous studies on other plants of the Chenopodiaceae family. For example, Gheraissa et al [34] found that Bassia muricata contains high levels of chlorogenic acid, gallic acid, p-coumaric acid, vanillic acid, and vanillin, which are also present in H. strobilaceum and S. fruticosa. Additionally, El-Beltagi et al [35] reported the presence of gallic acid, p-coumaric acid, and quercetin in Beta vulgaris L. root, which were also detected in H. strobilaceum and S. fruticosa.…”

“…Upon comparing the compounds present in the Chenopodiaceae family but not detected in the current study of H. strobilaceum and S. fruticosa, it can be observed that Bassia muricata contains gallic acid, vanillin, and naringin, which are absent in H. strobilaceum, and chlorogenic acid and naringin, which are absent in S. fruticosa extracts. These compounds have been reported to possess antioxidant and anti-inflammatory properties [34], indicating that the absence of these compounds in the studied plants may limit their potential as a source of these bioactive compounds.…”

Phytochemical profiling of Salsola tetragona Delile by LC-HR/MS and investigation of the antioxidant, anti-inflammatory, cytotoxic, antibacterial and anti-SARS-CoV-2 activities

“…The method of Gheraissa et al ( Gheraissa et al, 2022 ) was used with few modifications to explore the anti-inflammatory potential of S. tetragona samples in-vitro . Human albumin (5%), in a volume of 1 mL, was mixed with 1 mL of different samples concentrations and 20 mL of 1 N HCl.…”