Phenazines—V

Brock, D.J.H.; Holliman, F. G.

doi:10.1016/0040-4020(63)85006-1

Cited by 5 publications

(1 citation statement)

References 12 publications

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“…All other materials were reagent grade unless otherwise specified. 2-Carbomethoxy-3-nitro-benzoic acid, 9 2-carbomethoxy-3-nitro-benzoyl chloride, 2-azidocarbonyl-benzoic acid methyl ester, 10 2-amino-6-nitrobenzoic acid methyl ester, 11 2,6-diamino benzoic acid methyl ester, 12 2,6-dinitrobenzoic acid and 2,6-dinitrobenzoic acid methyl ester 13 were prepared according to literature methods.…”

Section: General Proceduresmentioning

confidence: 99%

Cysteine‐Specific Blue Fluorescence Probe

Reddy

Chang

2006

J Chinese Chemical Soc

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A strong fluorescence probe has been designed to investigate cytochrome c folding kinetics. The cysteine specific modifier, 2-[(-Iodo-acetyl)-methyl-amino]-6-methylaminobenzoic acid methyl ester (1), has been prepared, and the reaction with cysteine can be performed in aqueous solution to ensure its application to protein modification. The model compound, 2-{[2-(2-Acetylamino-2-methyoxycarbonylethylsulfanyl)-acetyl]-methyl-amino}-6-methyl amino-benzoic acid methyl ester (2), resulting from the reaction of 1 with N-acetyl cysteine has emission quantum yields of 0.627 and 0.185 in nonaqueous and aqueous buffer solutions, respectively. The lifetime of 4.6 ns for compound 2 manifests a singlet excited-state. The Förster energy transfer distance of compound 2 and cytochrome c is calculated to be 45 Å.

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Section: General Proceduresmentioning

confidence: 99%