Phemphigus Vulgaris (Pv) in Male Patient: A Case Report

Abstract

A 33Years Old male patient was admitted in Dermatology Department with chief complaints of fluid filled lesiosns all over the body since7 days patient was associated with 2.5 months back , then he developed lesions all over the body which are associated with itching burning and pain, also mouth lesions present . patient initially had lesions over forehead, neck, shoulder and slowly appeared all over the body , the blisters bursted on its own within 2-7days duration the lesions showed little tendency to heal increase in size and number present . patient gives history itching and burning prior to onset of lesions, no h/o lesions over other mucosa like eyes and genitals, no h/o raw areas at trauma mone area, no f/h/o blistering disease, no palm, sole involvement , no h/o insect bite. h/o application neem juice applica 2months back that is at intial stage, no h/o photosensitivity. h/o weight loss within 2 months about 10kg, h/o exacerbrations on alcohol consumption . when coming to past history patient was admitted for similar complaints for 19 days and gave treatment for him includes Inj decadran 2cc IM OD, for 13 days , T. Amoxyclav 625mg TID for 7days , Cap doxy 100mg OD for 10days, T.pantop 40mg OD, T. cetrizine 10mg OD, Cap A&D OD, T.B complex OD, T. Calcium OD ,T. IFA OD, Mupirocin ointment F/E/A Over erosions. Patient was admitted and taken treatment in the hospital for 38days.

Oral pemphigus vulgaris: A case report and review of the literature

“…Its global incidence rate was estimated around 0.2-3/100,000 persons/ year and expressed typically during the 5 th and 6 th decades of life with a male-to-female ratio of 1:2.2. [1,2] Pemphigus can be classified into six types: Pemphigus vulgaris, pemphigus vegetans, pemphigus erythematosus, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus that cause erosions and blisters of the skin and mucous membranes. The most common variant of this condition is pemphigus vulgaris accounting for 80% of the cases.…”

“…[1] The term "pemphix" is derived from the Greek root word "blister or pustule" and "vulgaris" from the Latin word "common" was originally named by Wichman in 1791. [1,2] It is characterized by the development of flaccid intraepithelial bullae that easily rupture creating areas of painful erosions and ulcerations. The oral cavity may present as the first site of involvement, so dentists must be able to recognize this condition and refer appropriately.…”