Phemphigoid gestationis

Veiga, Vera; Santos, Fernanda Gabriel; Antunes, A; Duarte, Isabel Margarida

doi:10.1136/bcr-2018-225242

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Therapeutic Options For Pemphigus and Pemphigoid Gestationis1

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2020

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“…The good safety profile during pregnancy and lactation and the effectiveness of these agents make low-dosage (less than 20 mg/day) ( Murase et al, 2014 ) systemic corticosteroids a first-line therapeutic option in this setting. Systemic corticosteroids, sometimes combined with topical corticosteroids, seem to be the mainstay also for PG treatment, particularly during pregnancy and in mild-to-moderate cases ( Piva et al, 2014 ; Veiga et al, 2018 ).…”

Section: Therapeutic Options For Pemphigus and Pemphigoid Gestationismentioning

confidence: 99%

Treatment of Autoimmune Bullous Diseases During Pregnancy and Lactation: A Review Focusing on Pemphigus and Pemphigoid Gestationis

et al. 2020

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Pregnancy may induce the onset or exacerbation of autoimmune bullous diseases such as pemphigus or pemphigoid gestationis. A shift toward T helper (Th) 2 immune response and the influence of hormonal changes have been evoked as possible triggering factors. Therapeutic management of this setting of patients may represent a challenge, mainly due to safety concerns of some immunosuppressive drugs during pregnancy and lactation. In this narrative review, we provided a comprehensive overview of the therapeutic management of autoimmune bullous diseases in pregnant and breastfeeding women, focusing on pemphigus and pemphigoid gestationis.

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Section: Therapeutic Options For Pemphigus and Pemphigoid Gestationismentioning

confidence: 99%