Abstract:OBJECTIVE:To compare the responsiveness of arthritisspecific and generic health outcome measures in relation to changes in the severity of osteoarthritis (OA). Clinical trial patients (n = 1,177) were assessed at baseline and again after two weeks of treatment. Criterion measures of change in severity included physician global assessment, knee pain on weight bearing, knee pain on motion, and patient global assessment.
METHODS:The responsiveness of each disease ‐specific and generic measure was estimated indepe… Show more
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