Phase variable colony variants are conserved across
Gardnerella
spp. and exhibit different virulence-associated phenotypes
Erin M. Garcia,
Amy K. Klimowicz,
Laahirie Edupuganti
et al.
Abstract:The
Gardnerella
genus, comprising at least 13 species, is associated with the polymicrobial disorder bacterial vaginosis (BV). However, the details of BV pathogenesis are poorly defined, and the contributions made by individual species, including
Gardnerella
spp., are largely unknown. We report here that colony phenotypes characterized by size (large and small) and opacity (opaque and translucent) are phase variable and are conserved among all tested
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