Phase studies of surfactant–water systems

Glycerol monooleate liquid crystalline phases used in drug delivery systems

“…80 Several review articles about lipid liquid crystalline phases have 81 been published to give insights into their structure and the 82 diversity of applications. The purpose of this review is to 83 summarize the data about drug delivery systems based on glycerol 84 monooleate liquid crystalline phases (Amar-Yuli et al, 2009;Caboi 85 et al, 2001;Chernik, 1999;Drummond and Fong, 1999;Engström, 86 1990;Fong et al, 2012;Garti et al, 2012;Guo et al, 2010;Hitesh 87 et al, 2011;Kaasgaard and Drummond, 2006;Kulkarni et al, 2011;88 Larsson, 2009;Leser et al, 2006;Sagalowicz et al, 2006a,b;Shah 89 et al, 2001). Furthermore, glycerol monooleate is a nontoxic, biodegradable 109 and biocompatible material, classified as GRAS (generally recog-110 nized as safe) and it is included in the FDA Inactive Ingredients 111 Guide (Bode et al, 2013;Ganem-Quintanar et al, 2000;Matschke 112 et al, 2002).…”

Liquid crystalline phase as a probe for crystal engineering of lactose: Carrier for pulmonary drug delivery

“…Glycerol 64 monooleate (GMO), a polar lipid is one of the metabolites of 65 triglycerides (Patton, 1979). It has been reported to form variety 66 of LC phases including reverse isotropic micellar solution (L 2 ), 67 lamellar (La), inverted type (reverse) hexagonal (H II ), and cubic 68 (V 2 ) having different physical properties and hence being explored 69 as a drug delivery systems including biomolecules (Chernik, 2000;70 Larsson, 1983;Qiu and Caffrey, 2000). However, to the best of our 71 knowledge utility of LC phases as one of the particle engineering 72 techniques has not yet been assessed.…”

The role of charged surfactants in the thermal and structural properties of lyotropic liquid crystalline mesophases of [Zn(H2O)6](NO3)2?CnEOm?H2O

“…The lyotropic liquid crystalline mesophase (LLCM) of oligo(ethylene oxide), C n H 2n+1 (OCH 2 CH 2 ) m OH (represented as C n EO m ) type surfactants with water [1][2][3] and water-oil [4,5] have been well established over the years. The water-C n EO m LLCM can accommodate transition metal salt (TMS) without disturbing the mesophase, denoted as TMS-water-C n EO m mesophase [6][7][8][9][10].…”