Phase separation of a nonionic surfactant aqueous solution in a standing surface acoustic wave for submicron particle manipulation

Zhao, Lei; Niu, Pengfei; Casals, Eudald; Zeng, Muling; Wu, Chuandong; Yang, Yang; Sun, Sheng; Zheng, Zongwei; Wang, Zhaoxun; Yuan, Ning; Duan, Xuexin

doi:10.1039/d0lc00986e

Cited by 12 publications

(6 citation statements)

References 26 publications

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“…For the intermittent migration pattern, the direction of the particle’s F r changes continuously and points to multiple pressure node lines (antinode line) successively, and the particle trajectory is almost a wavy line (the blue trace line in Figure c). The intermittent migration is also widespread in straight microchannels which have been widely reported by scholars. ,, The near-wall migration pattern means that the particles always move along the wall under the strong acoustic radiation force after entering the acoustic field, and their motion trajectory is a straight line (the green trace line in Figure c). The particle transverse migration distance of the intermittent migration pattern is small, and the particles are easy to stick to the wall in the near-wall migration pattern.…”

Section: Resultsmentioning

confidence: 58%

“…The intermittent migration is also widespread in straight microchannels which have been widely reported by scholars. 20,22,23 The near-wall migration pattern means that the particles always move along the wall under the strong acoustic radiation force after entering the acoustic field, and their motion trajectory is a straight line (the green trace line in Figure 7c). The particle transverse migration distance of the intermittent migration pattern is small, and the particles are easy to stick to the wall in the near-wall migration pattern.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

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Manipulation of Particle/Cell Based on Compressibility in a Divergent Microchannel by Surface Acoustic Wave

Xue

et al. 2023

Anal. Chem.

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The mechanical properties (compressibility or deformability) of cells are closely related to their death, migration, and differentiation. Accurate separation and manipulation of bioparticles based on these mechanical properties are still a challenging in the field of acoustofluidics. In this work, based on surface acoustic waves (SAW) and divergent microchannels, we developed a new method for separating and detecting particles or cells with different compressibility. The difference in acoustic radiation force (F r) caused by compressibility are gradually amplified and accumulated by decreasing the flow velocity, and they are finally reflected in the particle migration distance. During the transverse migration process, the alternating dominance of the acoustic radiation force and the Stokes resistance force (F s) drives the particles to create three typical migration patterns: intermittent migration, compound migration, and near-wall migration. In the present tilted SAW device, a 91% separation success rate of ∼10 μm polystyrene (PS) and polydimethylsiloxane (PDMS) particles can be achieved by optimizing the acoustic field input power and the fluid velocity. The application potential of the present divergent microchannel is validated by separating the myelogenous leukemia cell K562 and the natural killer cell NK92 that have similar densities and sizes (∼15 μm) but different compressibility. The results of this work are expected to provide valuable insights into the acoustofluidics separation and detection of the cells that are with different compressibility.

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Section: Resultsmentioning

confidence: 58%

Section: ■ Results and Discussionmentioning

confidence: 99%

Manipulation of Particle/Cell Based on Compressibility in a Divergent Microchannel by Surface Acoustic Wave

Xue

et al. 2023

Anal. Chem.

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“…In the acoustic streaming field, on the other hand, the acoustic streaming effect plays a dominant role, moving the fluid and particles within the chamber by generating significant F V . 47 Therefore, the relative direction and magnitude between F ARF and F V actually vary with the position of the chamber. However, since the densities (∼1080 kg m −3 ) of the particles and cells utilized in our experiments are larger than that of water (∼1000 kg m −3 ), and we sufficiently deposited the suspended particles/cells in the chamber prior to the excitation of the SAWs to optimize the manipulation performance, the majority of the particles/cells are actually in the stationary pressure field at the bottom of the chamber.…”

Section: Resultsmentioning

confidence: 99%

Bisymmetric coherent acoustic tweezers based on modulation of surface acoustic waves for dynamic and reconfigurable cluster manipulation of particles and cells

Pan

Mei

et al. 2023

Lab Chip

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“…18−20 Phase separation of a nonionic surfactant aqueous solution using a standing surface acoustic wave also exists. 21 The fractionation phenomenon or localized enrichment effect could occur during the electrospray process. For example, in situ and sequential separation of analytes from the spraying droplet was observed for the probe electrospray ionization (PESI).…”

Section: ■ Introductionmentioning

confidence: 99%

Formation of Alternating Surfactant-Enriched and Surfactant-Depleted Phases in the Taylor Cone of a Nanoelectrospray

Han,

Hishida,

Chen

2024

Anal. Chem.

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The electrospray ionization of highly conductive solutions containing Triton X-100, a nonionic surfactant, is found to induce alternating periods of surfactant enrichment and depletion when the concentration of the surfactant is near the critical micelle concentration (CMC) and when the flow rate is on the order of 10 nL/min. Analyzing the surfactant-protein mixture shows that the protein is partially denatured during the surfactant enrichment. The measurement of the phospholipid and oligosaccharide mixture prepared in the surfactant solution shows that the ion signal of the lipid is in phase with, and the hydrophilic oligosaccharide is out of phase with the surfactant signal. The results suggest that this novel phenomenon can be exploited for in situ separation of compounds in ESI-MS. Besides the ion signal, the condition of the alternating phase is also reflected in the spray current and Taylor cone's apex angle. The phase separation is likely related to the formation of a micelle in the Taylor cone and can be selectively triggered by tuning the flow rate with emitter voltage for an on-demand application.

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Phase separation of a nonionic surfactant aqueous solution in a standing surface acoustic wave for submicron particle manipulation

Abstract: Acoustic induced nanoparticle patterning and location migration in inhomogeneous media formed in situ.

Cited by 12 publications

References 26 publications

Manipulation of Particle/Cell Based on Compressibility in a Divergent Microchannel by Surface Acoustic Wave

Manipulation of Particle/Cell Based on Compressibility in a Divergent Microchannel by Surface Acoustic Wave

Bisymmetric coherent acoustic tweezers based on modulation of surface acoustic waves for dynamic and reconfigurable cluster manipulation of particles and cells

Formation of Alternating Surfactant-Enriched and Surfactant-Depleted Phases in the Taylor Cone of a Nanoelectrospray

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