Phase-Response Analysis of Stretch-Mediated Beat Coordination in the Oyster Heart. I. Phase-Response Characteristics of Auricle and Ventricle to Brief Stretches

Hiroyuki, Uesaka; Yamagishi, Hiroshi; Ebara, Arinobu

doi:10.2108/zsj.12.397

Cited by 1 publication

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“…Both agents were included in seawater, so the actual concentrations might be higher. For example, the artificial seawater already contains (in millimolar) 36 MgCl 2 , 17 MgSO 4 and 9 CaCl 2 (Uesaka, Yamagishi, & Ebara, ). Nevertheless, the seawater with enhanced Ca 2+ and Mg 2+ obliterated the spontaneous beats of the ventricle (Malyshev et al, ).…”

Section: Introductionmentioning

confidence: 99%

Limulus and heart rhythm

et al. 2018

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Great interest in the comparative physiology of hearts and their functions in Animalia has emerged with classic papers on Limulus polyphemus and mollusks. The recurrent cardiac activity-heart rate-is the most important physiological parameter and when present the kardia (Greek) is vital to the development of entire organs of the organisms in the animal kingdom. Extensive studies devoted to the regulation of cardiac rhythm in invertebrates have revealed that the basics of heart physiology are comparable to mammals. The hearts of invertebrates also beat spontaneously and are supplied with regulatory nerves: either excitatory or inhibitory or both. The distinct nerves and the source of excitation/inhibition at the level of single neurons are described for many invertebrate genera. The vertebrates and a majority of invertebrates have myogenic hearts, whereas the horseshoe crab L. polyphemus and a few other animals have a neurogenic cardiac rhythm. Nevertheless, the myogenic nature of heartbeat is precursor, because the contraction of native and stem-cellderived cardiomyocytes does occur in the absence of any neural elements. Even in L. polyphemus, the heart rhythm is myogenic at embryonic stages.

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Section: Introductionmentioning

confidence: 99%