2013
DOI: 10.7314/apjcp.2013.14.1.413
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Phase II Trial of Loubo®(Lobaplatin) and Pemetrexed for Patients with Metastatic Breast Cancer not Responding to Anthracycline or Taxanes

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Cited by 59 publications
(57 citation statements)
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“…Data are presented as means ± standard deviation (SD). We have enough experience in conducting medical researches, and have published some results elsewhere Dai et al, 2013;Deng et al, 2013;Gu et al, 2013;Fei et al, 2013;Shen et al, 2013;Sun et al, 2013;Wei et al, 2013;Yan et al, 2013;Gong et al, 2014;Zhang et al, 2014).…”
Section: Discussionmentioning
confidence: 99%
“…Data are presented as means ± standard deviation (SD). We have enough experience in conducting medical researches, and have published some results elsewhere Dai et al, 2013;Deng et al, 2013;Gu et al, 2013;Fei et al, 2013;Shen et al, 2013;Sun et al, 2013;Wei et al, 2013;Yan et al, 2013;Gong et al, 2014;Zhang et al, 2014).…”
Section: Discussionmentioning
confidence: 99%
“…In this way, LBP has shown good antitumour activity. In vivo, LBP remains good stability and low toxicity, some tumors resistanted to cisplatin are still sensitive to LBP.LBP has activity in a wider range of tumour types (McKeage, 2001;Wu, et al, 2010;Deng et al, 2013;Huang et al, 2013). LBP has been approved good inhibitory effect for the hepatocellular carcinoma cell lines (SMMC-27721, HepG2 and Bel2-7402) in the experiments in vitro (Qian et al, 2009).…”
Section: Discussionmentioning
confidence: 99%
“…Characterized by good water solubility, broad anti-tumor spectrum, strong anti-tumor activity, no achiasmate drug resistance with other platinum-based drugs and low toxicity, it exerts definite effects in the treatment of various tumors, such as breast cancer (Engel et al, 2012;Deng et al, 2013), lung cancer (Xie et al, 2012), esophageal carcinoma, gastrointestinal cancer and malignant pleural effusion and ascites. In terms of primary hepatic carcinoma, the in-vitro experimental studies have demonstrated that LBP has an inhibitory effect on hepatocellular carcinoma cells, and can be recommended to treat primary hepatic carcinoma in clinic (Qian et al, 2009;Wu et al, 2010;Wang et al, 2012).…”
Section: Discussionmentioning
confidence: 99%