Phase II Study of the Liposomal Formulation of Eribulin (E7389-LF) in Combination with Nivolumab: Results from the Gastric Cancer Cohort
Akihito Kawazoe,
Noboru Yamamoto,
Naotoshi Sugimoto
et al.
Abstract:Purpose: E7389-LF is a liposomal formulation of the microtubule dynamics inhibitor eribulin, and has shown preliminary efficacy in the treatment of gastric cancer (GC). Study 120, a phase 1b/2 open-label study, assessed efficacy and safety of E7389-LF in combination with nivolumab, a programmed cell death (PD)-1 inhibitor. This report focuses on the GC cohort of the expansion part. Patients and Methods: Eligible patients had unresectable, measurable GC, and progression following a platinum drug plus fluoropyri… Show more
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