Phase II prospective study of the use of conformal high-dose-rate brachytherapy as monotherapy for the treatment of favorable stage prostate cancer: A feasibility report

Martínez, Álvaro; Pataki, István; Edmundson, Gregory K.; Sebastian, Evelyn; Brabbins, D.; Gustafson, Gary

doi:10.1016/s0360-3016(00)01463-2

Cited by 242 publications

(154 citation statements)

References 26 publications

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“…The average displacement (4.1 mm) between the first and second fractions (on average, 19.5 hours difference) in this study is quite small as compared with the average displacement noted in several reports ( 9 – 12 ) in the literature. Using fluoroscopy, Martinez et al (9) measured a mean displacement of 20 mm between the first and second fractions (at least 6 hours difference, and 36 hours between the first and the fourth fractions).…”

Section: Discussioncontrasting

confidence: 85%

“…These four HDR fraction studies in the literature ( 9 – 12 ) showed time‐dependent catheter displacement between fractions. The maximum catheter displacement occurred up to approximately 12 hours after the first fraction (20 mm before the second fraction, (9) 7.6 mm before the second fraction, (10) and 6 mm before the third fraction (12) ).…”

Section: Discussionmentioning

confidence: 91%

“…The maximum catheter displacement occurred up to approximately 12 hours after the first fraction (20 mm before the second fraction, (9) 7.6 mm before the second fraction, (10) and 6 mm before the third fraction (12) ). Displacement magnitude subsequently decreased for the following fraction.…”

Section: Discussionmentioning

confidence: 97%

“…Using fluoroscopy, Martinez et al (9) measured a mean displacement of 20 mm between the first and second fractions (at least 6 hours difference, and 36 hours between the first and the fourth fractions). They reported that needle movement decreased between the subsequent fractions to an average of 4 mm (between the third and fourth fractions).…”

Section: Discussionmentioning

confidence: 99%

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Measurement of craniocaudal catheter displacement between fractions in computed tomography–based high dose rate brachytherapy of prostate cancer

Kim

Hsu

Pouliot

2007

J Applied Clin Med Phys

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The objective of the present work was to measure the craniocaudal displacement of catheters occurring between consecutive fractions of transrectal ultrasound (TRUS)‐guided high dose rate (HDR) prostate brachytherapy. Ten consecutive patients were treated with 2 fractions of 9.5‐Gy TRUS‐guided HDR brachytherapy, with dental putty being used for the fixation of catheters. For each patient, a computed tomography (CT) scan with 3‐mm slice thickness was acquired before each of the 2 fractions. Two different references were used to measure the catheter displacement between fractions: the ischial bone as a bony marker (BM) and the center of two gold markers (COGM) implanted in the prostate. Catheter displacement was calculated by multiplying the thickness of the CT slice by the difference in number of CT slices between the reference slice and the slice containing the tip of a catheter. The average magnitude of caudal catheter displacement was 2.7 mm (range: −6.0 mm to 13.5 mm) for the BM method and 5.4 mm (range: −3.75 mm to 18.0 mm) for the COGM method. The measurement data obtained from the BM and COGM methods verified that prostate movement and catheter displacement both occurred independently between fractions. The most anterior and medial two catheters (catheter positions 8 and 12) had the greatest tendency to be displaced in the caudal direction because they were located at the most distant position from the fulcrum, making them susceptible to rotation of the dental putty in the lateral plane because of the movement of the patients’ legs between fractions. In conclusion, the combination of the BM and COGM methods can demonstrate prostate and catheter movement relative to the BM between fractions. Our technique found a pattern of catheter displacement. Based on that finding, further improvement of our results may be possible by modification of our current technique.PACS number: 87.53.Jw

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Section: Discussioncontrasting

confidence: 85%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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Measurement of craniocaudal catheter displacement between fractions in computed tomography–based high dose rate brachytherapy of prostate cancer

Kim

Hsu

Pouliot

2007

J Applied Clin Med Phys

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“…Several authors have reported the benefits of using interstitial brachytherapy as an alternative to radical prostatectomy and external beam radiotherapy for the treatment of low and intermediate stage prostate cancer 1 , 2 , 3 , 4 . Results of multicenter studies 5 , 6 , 7 , 8 have shown that brachytherapy delivered as monotherapy or concurrently with external beam radiotherapy yields biochemical control rates similar to other techniques, while showing the lowest rates of long‐term complications to the organs at risk (OAR) (9) .…”

Section: Introductionmentioning

confidence: 99%

Comparison of IPSA and HIPO inverse planning optimization algorithms for prostate HDR brachytherapy

Panettieri

Smith

Mason

et al. 2014

J Applied Clin Med Phys

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Publications have reported the benefits of using high‐dose‐rate brachytherapy (HDRB) for the treatment of prostate cancer, since it provides similar biochemical control as other treatments while showing lowest long‐term complications to the organs at risk (OAR). With the inclusion of anatomy‐based inverse planning optimizers, HDRB has the advantage of potentially allowing dose escalation. Among the algorithms used, the Inverse Planning Simulated Annealing (IPSA) optimizer is widely employed since it provides adequate dose coverage, minimizing dose to the OAR, but it is known to generate large dwell times in particular positions of the catheter. As an alternative, the Hybrid Inverse treatment Planning Optimization (HIPO) algorithm was recently implemented in Oncentra Brachytherapy V. 4.3. The aim of this work was to compare, with the aid of radiobiological models, plans obtained with IPSA and HIPO to assess their use in our clinical practice. Thirty patients were calculated with IPSA and HIPO to achieve our department's clinical constraints. To evaluate their performance, dosimetric data were collected: Prostate PTV D90(%),V100(%),V150(%), and V200(%), Urethra D10(%), Rectum D2cc(%), and conformity indices. Additionally tumor control probability (TCP) and normal tissue complication probability (NTCP) were calculated with the BioSuite software. The HIPO optimization was performed firstly with Prostate PTV (HIPOPTV) and then with Urethra as priority 1 (HIPOurethra). Initial optimization constraints were then modified to see the effects on dosimetric parameters, TCPs, and NTCPs. HIPO optimizations could reduce TCPs up to 10%–20% for all PTVs lower than 74 cm3. For the urethra, IPSA and HIPOurethra provided similar NTCPs for the majority of volume sizes, whereas HIPOPTV resulted in large NTCP values. These findings were in agreement with dosimetric values. By increasing the PTV maximum dose constraints for HIPOurethra plans, TCPs were found to be in agreement with IPSA without affecting the urethral NTCPs.PACS numbers: 87.55.‐x, 87.55.de, 87.55.dh, 87.53.Jw

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Image‐guided Prostate Brachytherapy

Folkert

Desai

Yamada

2018

Smith's Textbook of Endourology

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Phase II prospective study of the use of conformal high-dose-rate brachytherapy as monotherapy for the treatment of favorable stage prostate cancer: A feasibility report

Cited by 242 publications

References 26 publications

Measurement of craniocaudal catheter displacement between fractions in computed tomography–based high dose rate brachytherapy of prostate cancer

Measurement of craniocaudal catheter displacement between fractions in computed tomography–based high dose rate brachytherapy of prostate cancer

Comparison of IPSA and HIPO inverse planning optimization algorithms for prostate HDR brachytherapy

Image‐guided Prostate Brachytherapy

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