Phase behaviour of room temperature ionic liquid solutions: an unusually large co-solvent effect in (water + ethanol)

Najdanovic‐Visak, Vesna; Esperança, José M. S. S.; Rebelo, Luís Paulo N.; Ponte, Manuel Nunes da; Guedes, Henrique J. R.; Seddon, Kenneth R.; Szydłowski, Jerzy

doi:10.1039/b201723g

Cited by 220 publications

(201 citation statements)

References 11 publications

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“…RTLs are being considered for selective extraction either in macro or micro scale. The isolation of target compounds from chemical process systems for instance alcohols from fermentation liquors (Chapeaux et al, 2008;Swatloski et al, 2002;Najdanovic-Visak et al, 2002), aromatic compounds from petroleum products (Arce et al, 2007a,b;Arce et al, 2009;Arce et al, 2008), aromatic sulfur-containing compounds (Mochizuki & Sugawara, 2008;Alonso et al, 2007;E er et al, 2004) from diesel-fuel represent the use of ILs in large-scale processes. In turn liquid-phase microextraction techniques such as dispersive, single-drop, hollowfiber based liquid-phase microextractions and solid-phase with liquid film represent miniaturized systems also utilizing ionic liquids as the extraction solvents.…”

Section: Liquid-liquid Extraction By Hydrophobic Ionic Liquidsmentioning

confidence: 99%

Ionic Liquids in Separation Techniques

Flieger¹,

Czajkowska-Żelazko²

2011

Applications of Ionic Liquids in Science and Technology

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Section: Liquid-liquid Extraction By Hydrophobic Ionic Liquidsmentioning

confidence: 99%

Ionic Liquids in Separation Techniques

Flieger¹,

Czajkowska-Żelazko²

2011

Applications of Ionic Liquids in Science and Technology

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“…[109][110][111][112][113][114][115][116][117][118] Ionic liquids are organic salts which are liquids at room temperature. Ionic liquids possess unique properties; they are not volatile or flammable and possess excellent chemical and thermal stability, 119 furthermore, they have been described as environmentally benign 120 which make them an attractive alternative to traditional organic solvents.…”

Section: Ionic Liquidsmentioning

confidence: 99%

Recent trends in whole cell and isolated enzymes in enantioselective synthesis

Milner¹,

Maguire²

2012

Arkivoc

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Modern synthetic organic chemistry has experienced an enormous growth in biocatalytic methodologies; enzymatic transformations and whole cell bioconversions have become generally accepted synthetic tools for asymmetric synthesis. This review details an overview of the latest achievements in biocatalytic methodologies for the synthesis of enantiopure compounds with a particular focus on chemoenzymatic synthesis in non-aqueous media, immobilisation technology and dynamic kinetic resolution. Furthermore, recent advances in ketoreductase technology and their applications are also presented.Keywords: Biocatalysis, kinetic and dynamic kinetic resolution, Baker's yeast, ketoreductases General IntroductionAsymmetric synthesis is the preferential formation of one stereoisomer of a chiral target compound to another; when scientists at GlaxoSmithKline, AstraZeneca and Pfizer 1 examined 128 syntheses from their companies, they found as many as half of the drug compounds made by their process research and development groups are not only chiral but also contain an average of two chiral centres each. 2In 2006 just 25 % were derived from the chiral pool and over 50 % employed chiral technologies. 1In order to meet regulatory requirements enantiomeric purities of 99.5 % were deemed necessary by the FDA. 3 This is one of the biggest challenges which face chemists today, primarily due to the recognition of the fact that different enantiomers of the same compound can interact differently in biological systems. As a consequence, the production of single enantiomers instead of racemic mixtures has become an important process in the pharmaceutical and agrochemical industry. Several routes can lead to the desired enantiomer including transition metal-, [4][5][6] organo-5,7-10 and bio-catalysis [11][12][13][14][15] and these have been thoroughly reviewed in the literature. 16,17 2. Biocatalysis IntroductionBiocatalysis involves the use of enzymes or whole cells (containing the desired enzyme or enzyme system) as catalysts for chemical reactions. A timeline of historic events in biocatalysis and biotechnology is outlined in Table 1. [18][19][20] Reviews and Accounts Novel methodologies for discovering industrial enzymes based on genomic sequencing and phage display (discussed further in Section 1.3), 21,22 as well as highly effective optimisation tools based on chemical, physical and molecular biology approaches, 23 have improved the access to biocatalysts, increased their stability, and radically broadened their specificity. 24This greater availability of catalysts with superior qualities including the use of new bioengineering tools contributed significantly to the development of new industrial processes. Biocatalytic methodologies for organic synthesis were outlined by Woodley et al. in three categories: established, emerging and expanding chemistries as depicted in Figure 1. 25 Enzyme classesBy the late 1950s it had become evident that the nomenclature of enzymes without any guiding authority, in a period when the...

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“…Room temperature ionic liquids (RTILs) have attracted increasing attention as the green, high-tech reaction media of the future. 28 RTILs have recently received a great deal of attention as potential new media for nanomaterials synthesis. [19][20][21][22][23][24][25] The most commonly used RTILs have PF 6 − and BF 4 − ions.…”

Section: Introductionmentioning

confidence: 99%

“…26 RTILs with these ions are known to decompose in the presence of water and as a result toxic and corrosive species such as hydrofluoric and phosphoric acids are formed. 28,29 The RTILs with alkyl sulfate anions are halogenfree and relatively hydrolysis-stable compounds and they could be an interesting alternative for industrial application due to the fact that they avoid the liberation of toxic and corrosive materials into the environment. 30 One of the largest barriers to the application of RTILs in various fields arises from their high cost relative to conventional solvents.…”

Section: Introductionmentioning

confidence: 99%

Facile and Room Temperature Preparation and Characterization of PbS Nanoparticles in Aqueous [EMIM][EtSO₄] Ionic Liquid Using Ultrasonic Irradiation

Behboudnia¹,

Habibi‐Yangjeh²,

Jafari-Tarzanag³

et al. 2009

Bulletin of the Korean Chemical Society

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At room-temperature, a facile, seedless, and environmentally benign green route for the synthesis of star like PbS nanoclusters at 7 min in aqueous solution of 1-ethyl-3-methylimidazolium ethyl sulfate, [EMIM] [EtSO4], room-temperature ionic liquid (RTIL), via ultrasonic irradiation is proposed. The X-ray diffraction studies display that the products are excellently crystallized in the form of cubic structure. An energy dispersive X-ray spectroscopy (EDX) investigation reveals the products are extremely pure. The absorption spectra of the product exhibit band gap energy of about 4.27 eV which shows an enormous blue shift of 3.86 eV that can be attributed to very small size of PbS nanoparticles produced and quantum confinement effect. A possible formation mechanism of the PbS nanoparticles using ultrasonic irradiation in aqueous solution of the RTIL is presented.

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Phase behaviour of room temperature ionic liquid solutions: an unusually large co-solvent effect in (water + ethanol)

Cited by 220 publications

References 11 publications

Ionic Liquids in Separation Techniques

Ionic Liquids in Separation Techniques

Recent trends in whole cell and isolated enzymes in enantioselective synthesis

Facile and Room Temperature Preparation and Characterization of PbS Nanoparticles in Aqueous [EMIM][EtSO₄] Ionic Liquid Using Ultrasonic Irradiation

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Phase behaviour of room temperature ionic liquid solutions: an unusually large co-solvent effect in (water + ethanol)

Cited by 220 publications

References 11 publications

Ionic Liquids in Separation Techniques

Ionic Liquids in Separation Techniques

Recent trends in whole cell and isolated enzymes in enantioselective synthesis

Facile and Room Temperature Preparation and Characterization of PbS Nanoparticles in Aqueous [EMIM][EtSO4] Ionic Liquid Using Ultrasonic Irradiation

Contact Info

Product

Resources

About

Facile and Room Temperature Preparation and Characterization of PbS Nanoparticles in Aqueous [EMIM][EtSO₄] Ionic Liquid Using Ultrasonic Irradiation