Phase Behavior and Froth Stability in a Water/Lysophospholipid System

Abstract

Phase behavior in a water/lysophospholipid system was investigated. A hydrated solid phase is observed at low temperature. Above the melting temperature of the hydrated solid a micellar phase at low surfactant concentration and a liquid crystalline phase at high surfactant concentration were observed. Similarly to poly(oxyethylene)-type nonionic surfactant systems, clouding behavior takes place at high temprature. The concentration of micelle-liquid crystal transition shifts to higher surfactant concentration in acidic or basic condition, but polyhydric alcohol addition does not affect very much on this transition point. The effect of added inorganic salts on the phase behavior was also studied, and the change in melting temperature of the hydrated solid and the cloud point shows a trend of the order of Hofmeister series. At room temperature a solid phase and an aqueous phase are equilibrated and one can obtain rather stable froth by shaking the sample that may be stabilized by the adsorption of solid dispersions on the air-water interface. The effect of inorganic salts on the froth stability in the water/lysophospholipid system was studied. The inorganic salts with salting-out effect improved froth stability.

A Study on the Formation of Liquid Ordered Phase in Lysophospholipid/Cholesterol/1,3-Butanediol/ Water and Lysophospholipid/Ceramide/1,3- Butanediol/Water Systems

“…A micellar phase appears at low LPL concentrations below 10 and a lamellar liquid crystalline phase appears at high concentrations. Below the Krafft point, a β-type hydrated solid is formed 21 but it changes to an α-type solid upon mixing with long-chain alcohols 22 . It has been shown that the effects of pH and of polyols and electrolytes, which are often added to cosmetics, on the phase behaviors of LPL/water systems are small 21 .…”

“…Below the Krafft point, a β-type hydrated solid is formed 21 but it changes to an α-type solid upon mixing with long-chain alcohols 22 . It has been shown that the effects of pH and of polyols and electrolytes, which are often added to cosmetics, on the phase behaviors of LPL/water systems are small 21 . It has also been reported that when an LPL was used as an emulsifier, the emulsions stability against electrolyte addition or pH change was improved 23,24 .…”

Cholesterol-Induced Formation of Liquid Ordered Phase–Like Structures in Non-Phospholipid Systems

“…It was hypothesized that lysophospholipid LPL , which is obtained by the hydrolysis of a phospholipid, can solubilize a larger amount of Chol in the molecular assembly than phospholipid, due to the shape of the molecule 25 . Therefore, we investigated the formation of an L o phase as a potential cosmetic base material in cosmetics by mixing Chol with lysophospholipid, which can dissolve a large amount of Chol and which exhibits a high moisturizing effect 26,27 .…”

Phase Behavior and Hydrated Solid Structure in Lysophospholipid/Long-chain Alcohol/Water System and Effect of Cholesterol Addition

“…It was reported that lysophopholipids have higher HLB value, lower surface tension and interfacial tension than phospholipids depending on the degree of hydrolysis, and these parameters become constant values when the degree of hydrolysis exceeds 80 11,12 . Krafft point and cloud point are present in the phase behavior of LPL/water system, where micellar phase appears at low concentration range less than 10 , lamellar liquid crystal phase appears at high concentration range above 10 , and lysophospholipid is found as β-type hydrated solid below Krafft point 13 . Moreover, it has also been verifi ed that effect of pH, polyol and electrolyte, which are often mixed with cosmetics, is small on the phase behavior in the LPL/ water system 13 .…”

“…Krafft point and cloud point are present in the phase behavior of LPL/water system, where micellar phase appears at low concentration range less than 10 , lamellar liquid crystal phase appears at high concentration range above 10 , and lysophospholipid is found as β-type hydrated solid below Krafft point 13 . Moreover, it has also been verifi ed that effect of pH, polyol and electrolyte, which are often mixed with cosmetics, is small on the phase behavior in the LPL/ water system 13 . In addition, it was reported that when lysophospholipid was used as emulsifier, emulsion stability against electrolyte or pH increased 14,15 .…”