Phase Behavior and Formation of Oleyl Ester Nanoemulsions System

Abstract

Oleylesters (OEs) are newly synthesized esters from different fatty acids of different chain length and oleyl alcohol using Novozyme 435 as catalyst. The phase behavior of these esters were determined by constructing the pseudoternaryphase diagrams of OEs/Tween 80/water at 25.0 ± 0.5°C. Compositions from the isotropic and homogeneous region were selected for characterization. The shortest OEs chain represents the most stable nanoemusions system with the smallest droplet for both isotropic and homogeneous regions. The results from simulation study showed that the shape of emulsion droplet was in spherical shape with the values of eccentricity (e) 0.11 to 0.17.

Molecular Dynamics Simulation of Palmitate Ester Self-Assembly with Diclofenac

“…The ternary phase diagram of OP/T80/water was experimentally determined by our research group [ 46 ]. We chose one spot from the isotropic region (20:50:30; OP:T80:W) for our simulations.…”